COPS6 and CDH10

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPS6	CDH10
Gene Name		COP9 signalosome subunit 6	cadherin 10, type 2 (T2-cadherin)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding
	Biological Process	Cullin Deneddylation Viral Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization
Pathways			Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS			β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Autism ( 19404256)
Protein-Protein Interactions		84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24	5 interactors: CDH6 CDH9 COPS6 JUP PTN
Entrez ID		10980	1008
HPRD ID		16735	05187
Ensembl ID		ENSG00000168090	ENSG00000040731
Uniprot IDs		Q7L5N1	Q9Y6N8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death	Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Endothelial Cell-cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Desmosome Assembly Cellular Response To Indole-3-methanol Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Adhesion Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Cullin Deneddylation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cytoskeletal Anchoring At Plasma Membrane Protein Deneddylation Regulation Of Cell Fate Specification Ventricular Cardiac Muscle Cell Action Potential Cellular Component Assembly Single Organismal Cell-cell Adhesion Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Cell Fate Commitment Epithelial Cell-cell Adhesion Cardiac Muscle Cell Action Potential Adherens Junction Assembly Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Detection Of Mechanical Stimulus Bone Mineralization
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	apc atlas capture characterisation col6a3 crc devised dock2 exome fat4 genomes kras mutated nevertheless next predicts prognostication recurrently sequencing signature silent smad4 somatic staging stratifying tmem132d tnm vcan verified
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	apc atlas capture characterisation col6a3 crc devised dock2 exome fat4 genomes kras mutated nevertheless next predicts prognostication recurrently sequencing signature silent smad4 somatic staging stratifying tmem132d tnm vcan verified
Tagcloud (Intersection) ?