COPS6 and ROGDI

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		COPS6	ROGDI
Description		COP9 signalosome subunit 6	rogdi atypical leucine zipper
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm	Nucleus Nuclear Envelope Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Cell Projection Perikaryon RAVE Complex Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse
	Molecular Function	Protein Binding Peptidase Activity Metal-dependent Deubiquitinase Activity	Protein Binding
	Biological Process	Protein Deneddylation Protein Neddylation Regulation Of Protein Neddylation	Regulation Of PH Brain Development Memory Locomotory Behavior Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Gene Expression Neurogenesis Hemopoiesis Bone Mineralization Locomotion Odontogenesis Of Dentin-containing Tooth Locomotor Rhythm PH Reduction Circadian Behavior Nervous System Process Neuromuscular Process Enamel Mineralization Amelogenesis
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Night sleep phenotypes ( 27126917)
Interacting Genes		95 interacting genes: ANXA1 ANXA7 ASH2L BFSP2 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCBE1 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CRIPTO CUL1 CUL5 DIS3L2 DLEU1 DSP EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 LAMA4 LPL MAP3K1 MAP7D1 MAPK1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SHANK3 SHC3 SLC2A1 SMN1 SNRPG STAMBPL1 STK40 STX5 SULT1E1 TK1 TP53 TP63 TRDMT1 TRIB3 UBC USHBP1 VIM WIPI2 ZEB2 ZFHX3 ZNF24	4 interacting genes: CEP126 CEP63 COPS6 DISC1
Entrez ID		10980	79641
HPRD ID		16735	13388
Ensembl ID		ENSG00000168090	ENSG00000067836
Uniprot IDs		Q7L5N1	Q9GZN7
PDB IDs		4D10 4D18 4QFT 4R14 4WSN 6R6H 6R7F 6R7H 6R7I 8H38 8H3A 8H3F	5XQH 5XQI
Enriched GO Terms of Interacting Partners?		Protein Neddylation Protein Deneddylation Regulation Of Protein Neddylation Nucleoplasm Heart Development COP9 Signalosome Developmental Process Cytosol Cellular Response To Staurosporine Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Metabolic Process Ubiquitin Protein Ligase Binding Signal Transduction By P53 Class Mediator Cellular Response To Nutrient Levels Protein Binding Positive Regulation Of Neuron Apoptotic Process Protease Binding Pyroptotic Inflammatory Response Protein Modification By Small Protein Removal Nucleus Animal Organ Development Regulation Of Cell Cycle G1/S Phase Transition Cytoplasm Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Developmental Process Cell Differentiation Macromolecule Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Keratinocyte Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Macromolecule Metabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Scaffold Protein Binding MAPK Cascade Cellular Response To Alkaloid Regulation Of Protein Modification Process Positive Regulation Of Programmed Cell Death Post-translational Protein Modification Protein Modification Process Regulation Of Post-translational Protein Modification Protein Tag Activity Cullin-RING Ubiquitin Ligase Complex Protein-containing Complex Cellular Response To Starvation Response To Nutrient Levels Mitotic G1 DNA Damage Checkpoint Signaling Rhythmic Synaptic Transmission G1/S Transition Of Mitotic Cell Cycle Mitotic G1/S Transition Checkpoint Signaling	Non-motile Cilium Assembly Microtubule Cytoskeleton Organization Ciliary Base Centrosome Organelle Assembly Microtubule-based Process Pyramidal Neuron Migration To Cerebral Cortex Cytoskeleton Organization Molecular Adaptor Activity Central Region Of Growth Cone Spindle Organization Regulation Of Post-translational Protein Modification Radial Glia-guided Pyramidal Neuron Migration Cilium Assembly Negative Regulation Of Protein K63-linked Ubiquitination De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Cilium Organization Cerebral Cortex Radial Glia-guided Migration Negative Regulation Of Protein Polyubiquitination Ciliary Basal Body Protein Deneddylation Regulation Of Protein Metabolic Process Cell Projection Assembly Cytoskeleton Plasma Membrane Bounded Cell Projection Assembly Metal-dependent Deubiquitinase Activity Regulation Of Protein K63-linked Ubiquitination Cell Proliferation In Forebrain Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cerebral Cortex Radially Oriented Cell Migration Regulation Of Protein Neddylation Protein Neddylation Detection Of Temperature Stimulus Involved In Sensory Perception Mitochondrial Calcium Ion Homeostasis Detection Of Temperature Stimulus Centriole Replication Protein Localization To Centrosome Positive Regulation Of Neuroblast Proliferation Glial Cell Migration Regulation Of Synapse Maturation Cerebral Cortex Cell Migration Regulation Of Protein Polyubiquitination Centriole Assembly Regulation Of Protein Modification Process COP9 Signalosome Dynein Complex Response To Electrical Stimulus Positive Regulation Of Axon Extension Proteolysis Involved In Protein Catabolic Process
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