COPS8 and USHBP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		COPS8	USHBP1
Gene Name		COP9 signalosome subunit 8	Usher syndrome 1C binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm COP9 Signalosome Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function		Protein Binding PDZ Domain Binding
	Biological Process	Activation Of NF-kappaB-inducing Kinase Activity Negative Regulation Of Cell Proliferation Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A CUL1 CUL5 DDB1 EIF3E GPS1 ITPK1 JUN MAPRE1 NFKBIA TP53 USHBP1	124 interactors: ABLIM1 AKAP9 ANKRD36BP1 ARFIP2 ARNT2 ATP5O BCL10 BET1 C10orf10 C1orf109 C1orf216 C6orf165 CCDC116 CCDC120 CCDC121 CCDC146 CCDC148 CCDC22 CCDC24 CCDC33 CCDC87 CCHCR1 CCNK CENPP CEP63 CEP68 CHCHD3 CNNM3 COPS4 COPS8 CTNNBIP1 CTTNBP2NL DTNB DYDC1 EIF4E2 ERCC1 EXOC7 EXOC8 FAM107A FAM110A FAM124B FANCG FATE1 FBF1 FTL GATAD2B GCC1 GFI1B GIT2 GMCL1P1 GNG4 GOLGA8EP GOLGA8F GPSM1 GPSM3 GTF2H1 HAUS1 HGS IFT20 IL16 IMP3 ING3 INPP1 INTS4 KANSL1 KIAA0753 KLC3 KLC4 KLHL38 KLHL42 KPNA2 KRT15 KRT19 KRT20 KRT31 KRT38 KRT40 KRT79 LENG1 LINC00526 MAGEB4 MCM7 MCRS1 MED28 MED4 MOS MRPS23 NCAPH2 NDC80 NDE1 NGFRAP1 NOC4L PARVG PMF1 PPP1R7 PPP2R5D PRC1 PRKAA2 RASAL2 RECK RIBC2 RNF20 SEC14L4 SERTAD3 SH2D4A SMARCD1 SMARCE1 STX11 SYNJ2BP THADA THOC1 TRIM54 TSG101 TUBGCP4 TXLNA TXLNB UBE2W UBXN11 USH1C VPS28 ZFYVE26 ZNF483 ZNF765 ZNRF2P1
Entrez ID		10920	83878
HPRD ID		16737	18276
Ensembl ID			ENSG00000130307
Uniprot IDs		Q99627	G8JLM4 Q8N6Y0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Protein Modification By Small Protein Removal Viral Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Cell Cycle Response To Abiotic Stimulus Protein Import Into Nucleus Apoptotic Signaling Pathway Nuclear Import Cell Proliferation Cell Cycle Arrest Protein Metabolic Process Protein Import Protein Import Into Nucleus, Translocation Release Of Cytochrome C From Mitochondria Cellular Macromolecule Catabolic Process Protein Localization To Nucleus Response To Radiation Circadian Rhythm Interaction With Symbiont Intrinsic Apoptotic Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Protein Localization To Organelle Modification-dependent Protein Catabolic Process Apoptotic Process Protein Monoubiquitination Programmed Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cell Death Negative Regulation Of DNA Binding Death Signal Transduction Toll-like Receptor 5 Signaling Pathway Protein Catabolic Process Toll-like Receptor 10 Signaling Pathway Regulation Of Binding Mitotic Cell Cycle Phase Transition Nucleocytoplasmic Transport Cell Cycle Phase Transition Nuclear Transport Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Response To UV Cellular Response To Potassium Ion Starvation Positive Regulation Of Neuron Apoptotic Process Toll-like Receptor 2 Signaling Pathway	Organelle Organization Cell Cycle Process Cell Cycle Cell Division Mitotic Cell Cycle Chromosome Organization Mitotic Cell Cycle Process Establishment Of Localization In Cell Cytoskeleton Organization Cellular Localization Microtubule-based Process Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification G2/M Transition Of Mitotic Cell Cycle Spindle Organization Regulation Of Metabolic Process Intracellular Transport Of Virus Intracellular Transport Mitotic Nuclear Division Centrosome Organization Cellular Process Cullin Deneddylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Establishment Of Spindle Orientation Microtubule Organizing Center Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Deneddylation Viral Protein Processing Establishment Of Cell Polarity Histone H4 Acetylation Spindle Localization Cellular Response To DNA Damage Stimulus Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Histone H4-K16 Acetylation Nucleosome Disassembly ATP-dependent Chromatin Remodeling Nucleotide-excision Repair, DNA Damage Removal Microtubule Nucleation Organelle Fusion Protein Targeting To Vacuole Virion Assembly
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