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COPS8
Gene Name
COP9 signalosome subunit 8
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Biological Process
Activation Of NF-kappaB-inducing Kinase Activity
Negative Regulation Of Cell Proliferation
Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
17 interactors:
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
CUL1
CUL5
DDB1
EIF3E
GPS1
ITPK1
JUN
MAPRE1
NFKBIA
TP53
USHBP1
Entrez ID
10920
HPRD ID
16737
Ensembl ID
Uniprot IDs
Q99627
PDB IDs
Enriched GO Terms of Interacting Partners
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Cullin Deneddylation
Protein Deneddylation
Protein Modification By Small Protein Removal
Viral Process
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Response To Abiotic Stimulus
Protein Import Into Nucleus
Apoptotic Signaling Pathway
Nuclear Import
Cell Proliferation
Cell Cycle Arrest
Protein Metabolic Process
Protein Import
Protein Import Into Nucleus, Translocation
Release Of Cytochrome C From Mitochondria
Cellular Macromolecule Catabolic Process
Protein Localization To Nucleus
Response To Radiation
Circadian Rhythm
Interaction With Symbiont
Intrinsic Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Protein Localization To Organelle
Modification-dependent Protein Catabolic Process
Apoptotic Process
Protein Monoubiquitination
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cell Death
Negative Regulation Of DNA Binding
Death
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Protein Catabolic Process
Toll-like Receptor 10 Signaling Pathway
Regulation Of Binding
Mitotic Cell Cycle Phase Transition
Nucleocytoplasmic Transport
Cell Cycle Phase Transition
Nuclear Transport
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Cellular Response To UV
Cellular Response To Potassium Ion Starvation
Positive Regulation Of Neuron Apoptotic Process
Toll-like Receptor 2 Signaling Pathway
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