COPS6 and TP53

  • Number of citations of the paper that reports this interaction (PMID 11285227)
  • 78
  • Data Source:
  • HPRD (in vitro)

COPS6

TP53

Gene Name COP9 signalosome subunit 6 tumor protein p53
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24 387 interactors: ABL1 ACTA1 AGT AIMP2 ANK2 ANKRD2 ANXA2 ANXA3 ANXA7 APEX1 APOH APTX ARID1A ARID3A ARIH2 ARL3 ASH2L ATF3 ATM ATR AURKA BACH1 BAIAP2L1 BAK1 BANP BARD1 BCL2 BCL2L1 BCL2L2 BCR BLM BMP1 BRCA1 BRCA2 BRF1 BTBD2 BTK C10orf90 CABLES1 CABLES2 CAPG CAPN1 CARM1 CCDC106 CCL18 CCNA2 CCNG1 CCNH CCT5 CD40LG CDC14A CDC14B CDC25C CDC42 CDK1 CDK2 CDK5 CDK7 CDK8 CDK9 CDKN2C CEBPZ CHD3 CHEK1 CHEK2 CHUK COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 COX17 CR2 CREBBP CSNK1A1 CSNK1D CSNK2A1 CSNK2B CUL9 CXXC1 DAPK3 DAXX DDB1 DDX5 DHCR24 DHFR DLEU1 DNAJC7 DVL2 E2F1 E4F1 EEF2 EFEMP2 EGR1 EHMT1 EHMT2 EIF2AK2 EIF2S2 ELL EP300 EPHA3 ERCC2 ERCC3 ERCC6 ERH ESR1 FAM173A FBXO11 FBXO42 FCAMR FXYD6 FZR1 GADD45A GNL3 GPS1 GPS2 GPX2 GSK3B GSTM4 GTF2H1 GTF2H4 HABP4 HDAC1 HDAC2 HDAC3 HECTD3 HECW1 HERC2 HIF1A HIPK1 HIPK2 HMGB1 HMGB2 HNF4A HNRNPUL1 HSP90AA1 HSP90AB1 HSPA1A HSPA9 HSPB1 HTT HUWE1 IFI16 IKBKB ING1 ING4 ING5 IRF7 ITPK1 KANSL1 KAT2B KAT5 KAT6A KAT7 KAT8 KDM1A KDM4D KIAA0087 KLF4 KLF6 KPNA2 KPNA4 KPNB1 LAMA4 MAD2L1BP MAGEA2 MAGEB18 MAPK1 MAPK10 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK5 MCL1 MDC1 MDH1 MDM2 MDM4 MED1 MED17 MED21 MEN1 MIF MNAT1 MNDA MPHOSPH6 MSL2 MSX1 MTA1 MTA2 MUC1 MUL1 MVP MYBBP1A NABP2 NAP1L1 NCL NCOA1 NCOA2 NCOA3 NDN NEDD8 NFKBIA NFYA NFYB NMT1 NMT2 NPM1 NQO1 NR0B2 NR3C1 NR4A1 OTUD5 PAFAH1B3 PARP1 PATZ1 PBK PCDHA4 PDLIM7 PER2 PHB PIAS1 PIAS2 PIAS4 PIN1 PLAGL1 PLK1 PLK3 PML PNP POLA1 PPA1 PPARGC1A PPM1D PPP1CA PPP1CC PPP1R13L PPP2CA PPP2R2B PPP4C PRIM1 PRKCA PRKD1 PRKDC PRKRA PRKRIR PRMT1 PSMB3 PSMC5 PSMD11 PSME3 PTEN PTGS2 PTK2 PTTG1 RAB4A RAD51 RANBP2 RANBP9 RAP1B RBBP5 RCC1 RCHY1 RFWD2 RNF128 RNF38 RPA1 RPS3 RRM2 RRM2B S100A2 S100A4 S100A6 S100A8 S100B SAT1 SCAMP1 SERPINB9 SET SETD1A SETD7 SETD8 SFN SHISA5 SIN3A SIN3B SIRT1 SMAD2 SMAD3 SMARCA4 SMARCB1 SMARCD1 SMN1 SMYD2 SNRPN SP1 SP3 SQSTM1 SRSF1 SSTR3 STAT6 STK11 STK4 STRA13 STX5 SULT1E1 SUMO1 SYVN1 TADA3 TAF1 TAF1A TAF1B TAF1C TAF9 TAF9B TBP TDG TEC TEP1 TFAP2A TFAP2C TFDP1 THAP8 THRB TK1 TOP1 TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TP53INP1 TP53RK TP63 TP73 TRIAP1 TRIM27 TRIM39 TSC22D1 TSC22D3 TSG101 TTK TXN UBB UBE2A UBE2D1 UBE2I UBE2J1 UBE2K UBE2M UBE2N UBE3A UBE4B UBR5 UFD1L UHRF2 UIMC1 USP10 USP42 USP7 UTP14A VPRBP VRK1 WDR33 WDR5 WDR82 WRN WT1 WWOX XAF1 XRCC6 YBX1 YWHAG YWHAZ YY1 ZBTB2 ZBTB7A ZCCHC10 ZHX1 ZMIZ2 ZNF148 ZNF24 ZNF302 ZNHIT1
Entrez ID 10980 7157
HPRD ID 16735 01859
Ensembl ID ENSG00000168090 ENSG00000141510
Uniprot IDs Q7L5N1 H2EHT1 K7PPA8 P04637 Q53GA5
PDB IDs 1A1U 1AIE 1C26 1DT7 1GZH 1H26 1HS5 1JSP 1KZY 1MA3 1OLG 1OLH 1PES 1PET 1SAE 1SAF 1SAK 1SAL 1TSR 1TUP 1UOL 1XQH 1YC5 1YCQ 1YCR 1YCS 2AC0 2ADY 2AHI 2ATA 2B3G 2BIM 2BIN 2BIO 2BIP 2BIQ 2F1X 2FEJ 2FOJ 2FOO 2GS0 2H1L 2H2D 2H2F 2H4F 2H4H 2H4J 2H59 2J0Z 2J10 2J11 2J1W 2J1X 2J1Y 2J1Z 2J20 2J21 2K8F 2L14 2LY4 2OCJ 2PCX 2VUK 2WGX 2X0U 2X0V 2X0W 2XWR 2YBG 2YDR 2Z5S 2Z5T 3D05 3D06 3D07 3D08 3D09 3D0A 3DAB 3DAC 3IGK 3IGL 3KMD 3KZ8 3LW1 3OQ5 3PDH 3Q01 3Q05 3Q06 3SAK 3TG5 3TS8 3ZME 4AGL 4AGM 4AGN 4AGO 4AGP 4AGQ 4BUZ 4BV2 4HFZ 4HJE 4IBQ 4IBS 4IBT 4IBU 4IBV 4IBW 4IBY 4IBZ 4IJT 4KVP 4LO9 4LOE 4LOF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aiming  aip  alignment  boar  brms1  chordc1  clues  csde1  csfv  ddx5  domestic  fever  gnb2l1  hemorrhagic  hspa8  interactive  metap2  nav1  ncbi  ns5a  phf5a  polr1c  ppp2r3c  psmc3  suvec  swine  tmed10  tmem70  y2h 
anchor  anchorage  artificial  assign  bac  backcross  bacs  bands  bovine  bta19  centromere  chrnb1  chromosomes  colour  construct  cryb1  fish  gh1  hybrid  interspecies  library  linkage  locations  loci  map  meiotic  nf1  p4hb  unresolved 
Tagcloud (Difference) ?
aiming  aip  alignment  boar  brms1  chordc1  clues  csde1  csfv  ddx5  domestic  fever  gnb2l1  hemorrhagic  hspa8  interactive  metap2  nav1  ncbi  ns5a  phf5a  polr1c  ppp2r3c  psmc3  suvec  swine  tmed10  tmem70  y2h 
anchor  anchorage  artificial  assign  bac  backcross  bacs  bands  bovine  bta19  centromere  chrnb1  chromosomes  colour  construct  cryb1  fish  gh1  hybrid  interspecies  library  linkage  locations  loci  map  meiotic  nf1  p4hb  unresolved 
Tagcloud (Intersection) ?