COPS6 and CCDC106

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPS6	CCDC106
Gene Name		COP9 signalosome subunit 6	coiled-coil domain containing 106
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm COP9 Signalosome Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cullin Deneddylation Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		84 interactors: ANXA1 ANXA7 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS8 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 JUN LAMA4 LPL MAP7D1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 VIM WIPI2 ZEB2 ZNF24	13 interactors: APP ATF4 C14orf1 COPS6 CRMP1 EEF1G FAM9B KAT5 LRIF1 RBM48 SETDB1 TP53 UTP14A
Entrez ID		10980	29903
HPRD ID		16735	09995
Ensembl ID		ENSG00000168090
Uniprot IDs		Q7L5N1	Q9BWC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Developmental Process Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Anatomical Structure Development Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Catalytic Activity Tissue Development Mitotic Cell Cycle Programmed Cell Death Apoptotic Signaling Pathway Response To Stress Cell Death Catabolic Process Death Regulation Of Cell Proliferation Mitotic Cell Cycle Process Cellular Response To Stress Response To Abiotic Stimulus G1/S Transition Of Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Phosphorylation Response To Organic Cyclic Compound Cell Cycle Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Cycle Organ Development Multicellular Organismal Development Epithelium Development Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Death Response To Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death System Development Negative Regulation Of Cell Death Cellular Macromolecule Catabolic Process Response To Organic Substance Regulation Of Protein Kinase Activity Positive Regulation Of Cell Death	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Cellular Response To Glucose Starvation RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Cellular Nitrogen Compound Metabolic Process Neuron Death Positive Regulation Of Neuron Death DNA Damage Response, Signal Transduction By P53 Class Mediator Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Response To External Stimulus Response To Oxidative Stress Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Macromitophagy Synaptic Growth At Neuromuscular Junction Oligodendrocyte Apoptotic Process Response To Radiation ER-nucleus Signaling Pathway Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Protein Metabolic Process Growth Cellular Metabolic Process Negative Regulation Of Helicase Activity Collateral Sprouting In Absence Of Injury Sterol Metabolic Process Positive Regulation Of Protein Metabolic Process Viral Process Cellular Response To Starvation Notch Signaling Pathway Response To Ionizing Radiation Double-strand Break Repair Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Growth Response To Endoplasmic Reticulum Stress Metabolic Process Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h
Tagcloud (Intersection) ?