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COPS8 and GPS1
Number of citations of the paper that reports this interaction (PMID
11337588
)
171
Data Source:
HPRD
(in vitro)
COPS8
GPS1
Gene Name
COP9 signalosome subunit 8
G protein pathway suppressor 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
COP9 Signalosome
Molecular Function
GTPase Inhibitor Activity
Protein Binding
Biological Process
Activation Of NF-kappaB-inducing Kinase Activity
Negative Regulation Of Cell Proliferation
Cullin Deneddylation
Inactivation Of MAPK Activity
Cell Cycle
JNK Cascade
Cullin Deneddylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
CUL1
CUL5
DDB1
EIF3E
GPS1
ITPK1
JUN
MAPRE1
NFKBIA
TP53
USHBP1
20 interactors:
COPS2
COPS3
COPS5
COPS6
COPS7A
COPS8
CUL1
CUL2
CUL3
CUL5
DDB1
IP6K1
ITPK1
JUN
RBX1
SENP8
SKP1
SKP2
TBC1D17
TP53
Entrez ID
10920
2873
HPRD ID
16737
15991
Ensembl ID
ENSG00000169727
Uniprot IDs
Q99627
C9JFE4
Q13098
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cullin Deneddylation
Protein Deneddylation
Protein Modification By Small Protein Removal
Viral Process
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Cell Cycle
Response To Abiotic Stimulus
Protein Import Into Nucleus
Apoptotic Signaling Pathway
Nuclear Import
Cell Proliferation
Cell Cycle Arrest
Protein Metabolic Process
Protein Import
Protein Import Into Nucleus, Translocation
Release Of Cytochrome C From Mitochondria
Cellular Macromolecule Catabolic Process
Protein Localization To Nucleus
Response To Radiation
Circadian Rhythm
Interaction With Symbiont
Intrinsic Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Protein Localization To Organelle
Modification-dependent Protein Catabolic Process
Apoptotic Process
Protein Monoubiquitination
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cell Death
Negative Regulation Of DNA Binding
Death
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Protein Catabolic Process
Toll-like Receptor 10 Signaling Pathway
Regulation Of Binding
Mitotic Cell Cycle Phase Transition
Nucleocytoplasmic Transport
Cell Cycle Phase Transition
Nuclear Transport
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Cellular Response To UV
Cellular Response To Potassium Ion Starvation
Positive Regulation Of Neuron Apoptotic Process
Toll-like Receptor 2 Signaling Pathway
Protein Deneddylation
Cullin Deneddylation
Protein Modification By Small Protein Removal
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein Monoubiquitination
Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Protein Modification Process
G1/S Transition Of Mitotic Cell Cycle
Proteolysis
Viral Process
Cellular Macromolecule Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Cell Cycle
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Metabolic Process
Cellular Protein Metabolic Process
Proteasomal Protein Catabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cell Cycle Arrest
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Catabolic Process
Mitotic Cell Cycle Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Metabolic Process
Mitotic Cell Cycle
Notch Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Circadian Rhythm
Cell Cycle Process
Negative Regulation Of Cell Proliferation
Regulation Of Cell Proliferation
Regulation Of DNA-templated Transcription In Response To Stress
Response To Abiotic Stimulus
Cell Communication
Metabolic Process
Negative Regulation Of Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Signal Transduction
Histone H2A Monoubiquitination
Cell Cycle
Histone H2A Ubiquitination
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Signaling
Tagcloud
?
abnormal
assigned
calculated
cop
count
css
escc
esophageal
esophagectomy
follows
glasgow
gps0
gps2
hypoalbuminemia
indexes
kaplan
log
lymphocyte
meier
neutrophil
nlr
nlr0
nlr1
nlr2
platelet
predicts
prognostic
rank
Tagcloud (Difference)
?
abnormal
assigned
calculated
cop
count
css
escc
esophageal
esophagectomy
follows
glasgow
gps0
gps2
hypoalbuminemia
indexes
kaplan
log
lymphocyte
meier
neutrophil
nlr
nlr0
nlr1
nlr2
platelet
predicts
prognostic
rank
Tagcloud (Intersection)
?