CHERP and WBP4

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		CHERP	WBP4
Gene Name		calcium homeostasis endoplasmic reticulum protein	WW domain binding protein 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Spliceosomal Complex Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding Ion Channel Binding Poly(A) RNA Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of NFAT Protein Import Into Nucleus	MRNA Cis Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		28 interactors: AGGF1 APBB1 ARGLU1 CCAR1 EWSR1 FRA10AC1 GNB2L1 HNRNPH3 LUC7L PPIL4 PRPF38A PRPF40A RBM23 RBM39 RBM7 RNPS1 SART1 SF3B4 SNIP1 SNRNP27 SNRNP70 SRPK1 SRPK2 TTC14 U2AF1 U2AF2 UBC WBP4	44 interactors: BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DIAPH1 DNM2 EFTUD2 EWSR1 FUS HLTF HNRNPK HNRNPU HTATSF1 KHDRBS1 NONO PABPC1 PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B3 SF3B4 SFPQ SNRNP70 SNRPA SNRPB TCERG1 WAS WBP11 WIPF1 XRCC6 ZNF207
Entrez ID		10523	11193
HPRD ID		13051	16086
Ensembl ID		ENSG00000085872	ENSG00000120688
Uniprot IDs		J3QK89 Q8IWX8	B7Z4M2 O75554
PDB IDs			2DK1 2JXW
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Cellular Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Negative Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Positive Regulation Of Viral Genome Replication Nuclear Export MRNA Transport Positive Regulation Of Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Transcription, DNA-templated Positive Regulation Of Cell Death Cellular Process RNA Transport RNA Localization RNA Biosynthetic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Maturation Of 5S RRNA Negative Regulation Of Thymidylate Synthase Biosynthetic Process	MRNA Processing RNA Splicing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly MRNA 3'-splice Site Recognition Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Cellular Component Assembly MRNA Splice Site Selection Cellular Process Metabolic Process MRNA 3'-end Processing Transcription, DNA-templated RNA Biosynthetic Process RNA 3'-end Processing Spliceosomal SnRNP Assembly Posttranscriptional Regulation Of Gene Expression Attachment Of Spindle Microtubules To Kinetochore Rhythmic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Translational Initiation Macromolecule Biosynthetic Process Positive Regulation Of Translation Actin Polymerization Or Depolymerization Negative Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Circadian Rhythm Regulation Of RNA Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Positive Regulation Of Gene Expression MRNA Polyadenylation Cellular Response To Osmotic Stress
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