CHERP and CCAR1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		CHERP	CCAR1
Gene Name		calcium homeostasis endoplasmic reticulum protein	cell division cycle and apoptosis regulator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ion Channel Binding Poly(A) RNA Binding	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Poly(A) RNA Binding
	Biological Process	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of NFAT Protein Import Into Nucleus	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AGGF1 APBB1 ARGLU1 CCAR1 EWSR1 FRA10AC1 GNB2L1 HNRNPH3 LUC7L PPIL4 PRPF38A PRPF40A RBM23 RBM39 RBM7 RNPS1 SART1 SF3B4 SNIP1 SNRNP27 SNRNP70 SRPK1 SRPK2 TTC14 U2AF1 U2AF2 UBC WBP4	10 interactors: CASP10 CHERP GOLGA2 HNRNPK MDM2 PIH1D3 RBM10 RNF113A SFN U2AF2
Entrez ID		10523	55749
HPRD ID		13051	10811
Ensembl ID		ENSG00000085872	ENSG00000060339
Uniprot IDs		J3QK89 Q8IWX8	Q8IX12
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Cellular Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Negative Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Positive Regulation Of Viral Genome Replication Nuclear Export MRNA Transport Positive Regulation Of Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Transcription, DNA-templated Positive Regulation Of Cell Death Cellular Process RNA Transport RNA Localization RNA Biosynthetic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Maturation Of 5S RRNA Negative Regulation Of Thymidylate Synthase Biosynthetic Process	Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Intracellular Protein Transport RNA Processing Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Export From Nucleus Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Regulation Of Intracellular Protein Transport Positive Regulation Of Protein Transport RNA Splicing Cellular Response To UV-C Cellular Response To Vitamin B1 MRNA Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Intracellular Transport Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter MRNA Metabolic Process Regulation Of Epidermal Cell Division Regulation Of Protein Transport Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Establishment Of Protein Localization Response To Vitamin B1 Response To Ether Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Localization Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of NFAT Protein Import Into Nucleus Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Response To UV-C Keratinocyte Development Negative Regulation Of Endopeptidase Activity Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Peptidase Activity Apoptotic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Programmed Cell Death Regulation Of Cellular Localization Axonemal Dynein Complex Assembly Cell Death Death Regulation Of Receptor Biosynthetic Process Establishment Of Skin Barrier
Tagcloud ?			alleles architecture cdkn1b chd1 copy damaging drivers encompassing exome foxa1 genotyping heterozygosity interpret interpretation kip1 loh manage mosaicism mutational personalized rb1 retained scpc somatic suppressors tp53 underscores virchow widespread
Tagcloud (Difference) ?			alleles architecture cdkn1b chd1 copy damaging drivers encompassing exome foxa1 genotyping heterozygosity interpret interpretation kip1 loh manage mosaicism mutational personalized rb1 retained scpc somatic suppressors tp53 underscores virchow widespread
Tagcloud (Intersection) ?