CHERP and SNRNP27

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CHERP	SNRNP27
Gene Name		calcium homeostasis endoplasmic reticulum protein	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Cellular_component Precatalytic Spliceosome
	Molecular Function	Protein Binding Ion Channel Binding Poly(A) RNA Binding	Nucleic Acid Binding Protein Binding
	Biological Process	RNA Processing Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of NFAT Protein Import Into Nucleus	MRNA Processing Biological_process RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AGGF1 APBB1 ARGLU1 CCAR1 EWSR1 FRA10AC1 GNB2L1 HNRNPH3 LUC7L PPIL4 PRPF38A PRPF40A RBM23 RBM39 RBM7 RNPS1 SART1 SF3B4 SNIP1 SNRNP27 SNRNP70 SRPK1 SRPK2 TTC14 U2AF1 U2AF2 UBC WBP4	3 interactors: CHERP DHX16 SRPK2
Entrez ID		10523	11017
HPRD ID		13051	15288
Ensembl ID		ENSG00000085872
Uniprot IDs		J3QK89 Q8IWX8	A8K513 Q8WVK2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Cellular Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Negative Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Positive Regulation Of Viral Genome Replication Nuclear Export MRNA Transport Positive Regulation Of Apoptotic Process Regulation Of Cell Cycle Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Transcription, DNA-templated Positive Regulation Of Cell Death Cellular Process RNA Transport RNA Localization RNA Biosynthetic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Viral Genome Replication Nuclear Speck Organization Maturation Of 5S RRNA Negative Regulation Of Thymidylate Synthase Biosynthetic Process	RNA Processing Nuclear Speck Organization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Positive Regulation Of NFAT Protein Import Into Nucleus MRNA Processing MRNA Metabolic Process RNA Metabolic Process Positive Regulation Of Viral Genome Replication Gene Expression Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Viral Genome Replication Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Nucleobase-containing Compound Metabolic Process Positive Regulation Of Neuron Apoptotic Process Spliceosomal Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Neuron Death Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of Cell Proliferation Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Regulation Of RNA Splicing Nitrogen Compound Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus
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