CHERP and RBM23

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		CHERP	RBM23
Description		calcium homeostasis endoplasmic reticulum protein	RNA binding motif protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleus Membrane
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Transmembrane Transporter Binding	Nucleic Acid Binding RNA Binding Protein Binding U1 SnRNP Binding
	Biological Process	RNA Processing Intracellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade	MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MECOM MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 USP54 WBP4	31 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 KHDC4 MAGEA11 MAGED1 MED31 OGT PGR POLA2 PRMT5 PRR20A PRR20B PRR20C PRR20D PRR20E PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 TRIM27 TUBA4A
Entrez ID		10523	55147
HPRD ID		13051	15227
Ensembl ID		ENSG00000085872	ENSG00000100461
Uniprot IDs		Q8IWX8	A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06
PDB IDs			2CQ4 2DNZ
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Regulation Of MRNA Splicing, Via Spliceosome MiRNA-mediated Post-transcriptional Gene Silencing Nucleic Acid Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Nuclear Speck Regulation Of MRNA Processing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RNA Metabolic Process Spliceosomal Complex RS Domain Binding U1 SnRNP Binding Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MRNA Cis Splicing, Via Spliceosome U2-type Precatalytic Spliceosome U2-type Prespliceosome Negative Regulation Of Macromolecule Biosynthetic Process U1 SnRNP Precatalytic Spliceosome Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Extracellular Vesicle Nucleobase-containing Compound Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Gene Expression	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Rhythmic Process Regulation Of RNA Splicing Circadian Regulation Of Gene Expression Nucleoplasm Regulation Of MRNA Metabolic Process RNA Splicing Circadian Rhythm Nucleic Acid Binding Positive Regulation Of Oligodendrocyte Differentiation MRNA Processing RNA Metabolic Process Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Regulation Of RNA Metabolic Process MRNA Metabolic Process RNA Processing Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleus Estrogen Response Element Binding Positive Regulation Of Gliogenesis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Glial Cell Differentiation Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Protein-containing Complex Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of Fibroblast Proliferation Nuclear Steroid Receptor Activity Cell Development Estrogen Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Regulation Of Gliogenesis Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process Steroid Binding Photoperiodism Regulation Of Circadian Rhythm Entrainment Of Circadian Clock MRNA Binding Negative Regulation Of Hemopoiesis Negative Regulation Of Cell Development
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