CHERP and FASTK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CHERP	FASTK
Description		calcium homeostasis endoplasmic reticulum protein	Fas activated serine/threonine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Transmembrane Transporter Binding	Nucleotide Binding RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Fas-activated Serine/threonine Kinase Activity Protein Serine Kinase Activity
	Biological Process	RNA Processing Intracellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade	Mitochondrial RNA Processing Protein Phosphorylation Apoptotic Process Regulation Of RNA Splicing Regulation Of Mitochondrial MRNA Stability Apoptotic Signaling Pathway
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Eyebrow thickness ( 26926045)
Interacting Genes		48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MECOM MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 USP54 WBP4	9 interacting genes: CALCOCO2 CHERP ESRRG MDFI PRPF31 RBPMS TIA1 TOP3B WIPF1
Entrez ID		10523	10922
HPRD ID		13051	07368
Ensembl ID		ENSG00000085872	ENSG00000164896
Uniprot IDs		Q8IWX8	A0A090N8I0 A0A090N8Z7 Q14296
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Regulation Of MRNA Splicing, Via Spliceosome MiRNA-mediated Post-transcriptional Gene Silencing Nucleic Acid Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Nuclear Speck Regulation Of MRNA Processing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RNA Metabolic Process Spliceosomal Complex RS Domain Binding U1 SnRNP Binding Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MRNA Cis Splicing, Via Spliceosome U2-type Precatalytic Spliceosome U2-type Prespliceosome Negative Regulation Of Macromolecule Biosynthetic Process U1 SnRNP Precatalytic Spliceosome Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Extracellular Vesicle Nucleobase-containing Compound Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Gene Expression	RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Binding RNA Topoisomerase Activity Ribonucleoprotein Complex Localization Cytoplasmic Stress Granule DNA Topoisomerase III-beta-TDRD3 Complex U4atac SnRNP AF-2 Domain Binding Regulation Of MRNA Processing MRNA 3'-UTR Binding Regulation Of MRNA Splicing, Via Spliceosome DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity MRNA CDS Binding SnRNP Binding U4atac SnRNA Binding Nucleic Acid Binding SnoRNA Localization
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