PDE4DIP and ZNF512B

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		PDE4DIP	ZNF512B
Gene Name		phosphodiesterase 4D interacting protein	zinc finger protein 512B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Nucleus
	Molecular Function	Protein Binding Enzyme Binding	DNA Binding Metal Ion Binding
	Biological Process	Cellular Protein Complex Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933)	Prostate cancer ( 23535732)
Protein-Protein Interactions		64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	60 interactors: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FAM129B FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2
Entrez ID		9659	57473
HPRD ID		10482	13840
Ensembl ID		ENSG00000178104	ENSG00000196700
Uniprot IDs		F8WAP3 Q5VU43	Q96KM6
PDB IDs			2GQJ
Enriched GO Terms of Interacting Partners?		Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction	Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organ Development System Development Transcription, DNA-templated Developmental Process Chromosome Organization Anatomical Structure Development Regulation Of Gene Expression RNA Biosynthetic Process Response To Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Negative Regulation Of Biosynthetic Process Cell Cycle Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Cycle Process Multicellular Organismal Development Viral Genome Replication Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Organization Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Chromatin Remodeling RNA Metabolic Process Primary MiRNA Processing Vesicle-mediated Transport Endosomal Transport Regulation Of Signal Transduction Cellular Response To Stress Mitotic Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter
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