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PDE4DIP and TRAF4
Number of citations of the paper that reports this interaction (PMID
16969126
)
5
Data Source:
BioGRID
(two hybrid)
PDE4DIP
TRAF4
Gene Name
phosphodiesterase 4D interacting protein
TNF receptor-associated factor 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Centrosome
Myofibril
Nucleus
Cytoplasm
Cytoskeleton
Plasma Membrane
Tight Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Enzyme Binding
DNA Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
WW Domain Binding
Biological Process
Cellular Protein Complex Assembly
Apoptotic Process
Signal Transduction
Activation Of NF-kappaB-inducing Kinase Activity
Respiratory Gaseous Exchange
Protein Ubiquitination
Respiratory Tube Development
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Positive Regulation Of Protein Homodimerization Activity
Pathways
Drugs
Diseases
GWAS
Capecitabine sensitivity (
22864933
)
Protein-Protein Interactions
64 interactors:
ADH1B
AEN
ANKRD11
ARNT2
BYSL
C14orf105
C19orf66
C1orf109
CCDC146
CDC5L
CDKN1A
CHCHD3
FAM161A
FAM74A4
FCHSD2
FES
FHL1
GADD45G
GFI1B
GOLGA8EP
GOLGA8F
HAUS1
IMMT
ITSN2
KDM1A
KLC3
KLC4
KRAS
KRT18
KRT31
LAMTOR3
LENG1
LMO4
MAPRE1
MIF4GD
MTUS2
NAA10
NEFL
NEK2
OSGEP
PDE4D
PFDN1
PIAS4
PPP1R18
PRNP
PRPF31
RTP5
SCNM1
SDCBP
SH2D4A
SMN1
SNCA
TFIP11
TK1
TNIK
TRAF4
UTP14C
VAC14
ZBTB38
ZFYVE21
ZNF408
ZNF512B
ZNF581
ZSCAN26
69 interactors:
ALKBH4
ARNT2
BAHD1
BANP
BCKDK
BCL6B
BYSL
CALCOCO2
CBL
CBLC
CCHCR1
CENPE
CHUK
DTX3
EXOC7
FBXL18
FTH1
GORASP2
GPRASP1
HOMEZ
IRAK1
ISYNA1
KANSL1
KDM1A
KRT31
KRT40
LTBR
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NGFRAP1
NOS1AP
NPAS2
PDE4DIP
PKD1P1
PLSCR1
PSMC3
QARS
REXO1L6P
RNF114
RPS6KB1
SIGLEC7
SMURF1
SMURF2
SORBS2
SPDL1
SUMO1
TARBP2
TBC1D7
TBC1D8
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM37
TYK2
UBE2I
UBL4A
UBL4B
USP7
WBP11
WWP1
WWP2
ZNF3
ZNF512B
ZNF581
Entrez ID
9659
9618
HPRD ID
10482
03915
Ensembl ID
ENSG00000178104
ENSG00000076604
Uniprot IDs
F8WAP3
Q5VU43
Q9BUZ4
PDB IDs
2EOD
2YUC
4M4E
Enriched GO Terms of Interacting Partners
?
Developmental Process
Response To Copper Ion
RNA Metabolic Process
Anatomical Structure Development
Nucleobase-containing Compound Metabolic Process
Regulation Of Microtubule Polymerization
Multicellular Organismal Development
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Response To Copper Ion
Response To Mineralocorticoid
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of JNK Cascade
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Cell Death
Regulation Of Phosphorylation
Response To Glucocorticoid
Regulation Of JNK Cascade
Activation Of MAPKK Activity
Positive Regulation Of Protein Kinase Activity
Nitrogen Compound Metabolic Process
Response To Corticosteroid
Regulation Of Metabolic Process
Regulation Of Microtubule-based Process
Negative Regulation Of Microtubule Polymerization
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Kinase Activity
Regulation Of Microtubule Polymerization Or Depolymerization
Cellular Response To Epinephrine Stimulus
Regulation Of Cellular Component Organization
System Development
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Response To Epinephrine
RNA Splicing
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cell Death
Positive Regulation Of Transferase Activity
Regulation Of Histone H3-K4 Methylation
Regulation Of Kinase Activity
Embryo Development Ending In Birth Or Egg Hatching
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Intracellular Signal Transduction
Protein Modification By Small Protein Conjugation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Ubiquitination
Regulation Of Gene Expression
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Signaling
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Response To Growth Factor
Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Cellular Protein Modification Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Response To Organic Substance
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Cytokine
Cellular Protein Catabolic Process
Cell Death
Death
Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Protein Catabolic Process
Tagcloud
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Difference)
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Intersection)
?