PDE4DIP and CCDC198

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PDE4DIP	CCDC198
Description		phosphodiesterase 4D interacting protein	coiled-coil domain containing 198
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytoskeleton Myofibril Cortical Microtubule Plus-end	Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Centrosome Cycle Astral Microtubule Organization Protein-containing Complex Assembly Positive Regulation Of Microtubule Nucleation Regulation Of Golgi Organization	Energy Homeostasis
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)
Interacting Genes		88 interacting genes: ADH1B AEN AIRIM AKTIP ANKRD11 ARNT2 BYSL CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CLIP4 CWF19L2 DSCAM DSCR9 EGR2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RSPH1 RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 TK1 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26	27 interacting genes: CBY2 FAM9B FHL2 FHL3 FKBP6 GOLGA2 GOPC HOOK2 HSF2BP IQGAP3 KIFC3 KRT31 KRT34 KRT40 LZTS2 MDFI MTUS2 PDE4DIP PFDN5 PNMA1 SIAH1 SMAD3 SSX2IP TEX11 TRAF1 TRAF2 TRIM27
Entrez ID		9659	55195
HPRD ID		10482	12628
Ensembl ID		ENSG00000178104	ENSG00000100557
Uniprot IDs		A0A075B749 A0A8Q3SI21 A0A8Q3SI83 A0A8Q3WM32 A0A994J5E0 E9PQG4 Q5VU43	B7ZL43 E9PSE9 F5GWJ3 Q05C89 Q9NVL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Zinc Ion Binding Nucleus Cytoskeleton Organization Cytoskeleton Protein Binding DNA-binding Transcription Factor Activity	Identical Protein Binding Supramolecular Fiber Organization Synaptonemal Complex Cytoplasm Organelle Organization Cytoskeleton Centrosome Cycle Cytoskeleton Organization Structural Constituent Of Skin Epidermis Thioesterase Binding Microtubule Intermediate Filament Organization Microtubule Organizing Center Organization Developmental Process Involved In Reproduction Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Centrosome Microtubule Binding Reproductive Process BHLH Transcription Factor Binding Meiotic Cell Cycle Protein Binding Microtubule-based Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding RNA Polymerase III Assembly RNA Polymerase I Assembly Tumor Necrosis Factor Receptor Binding TORC2 Complex Disassembly Meiotic Gene Conversion Negative Regulation Of Anion Channel Activity Primary Ureteric Bud Growth Myosin VI Light Chain Binding Morphogenesis Of An Epithelium Signal Transduction Involved In Regulation Of Gene Expression Intermediate Filament
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