PDE4DIP and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PDE4DIP	PPP1R18
Description		phosphodiesterase 4D interacting protein	protein phosphatase 1 regulatory subunit 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytoskeleton Myofibril Cortical Microtubule Plus-end	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Centrosome Cycle Astral Microtubule Organization Protein-containing Complex Assembly Positive Regulation Of Microtubule Nucleation Regulation Of Golgi Organization
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)	Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease ( 33909500) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		88 interacting genes: ADH1B AEN AIRIM AKTIP ANKRD11 ARNT2 BYSL CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CLIP4 CWF19L2 DSCAM DSCR9 EGR2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RSPH1 RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 TK1 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		9659	170954
HPRD ID		10482	11172
Ensembl ID		ENSG00000178104	ENSG00000146112
Uniprot IDs		A0A075B749 A0A8Q3SI21 A0A8Q3SI83 A0A8Q3WM32 A0A994J5E0 E9PQG4 Q5VU43	A0A024RCJ8 A0A0G2JHC2 Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Zinc Ion Binding Nucleus Cytoskeleton Organization Cytoskeleton Protein Binding DNA-binding Transcription Factor Activity	Cytoskeleton Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Organelle Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Keratin Filament Structural Constituent Of Cytoskeleton Structural Molecule Activity Protein Binding Identical Protein Binding Intermediate Filament Cytoskeleton Microtubule-based Process Centrosome Morphogenesis Of An Epithelium Microtubule Cytoskeleton Organization Tissue Morphogenesis Cytosol Cytoplasm Microtubule Organizing Center Bergmann Glial Cell Differentiation Epithelial Cell Differentiation Microtubule Organizing Center Organization Negative Regulation Of Viral Transcription Intracellular Transport Developmental Process Regulation Of Viral Transcription Response To Muramyl Dipeptide Cellular Developmental Process Positive Regulation Of Skeletal Muscle Tissue Growth Establishment Of Localization In Cell Developmental Process Involved In Reproduction Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Cytoskeleton-dependent Intracellular Transport Kinetochore Binding Regulation Of Autophagy Cell Differentiation Regulation Of Skeletal Muscle Tissue Growth Z Disc Intracellular Protein Localization Protein Transport Astrocyte Differentiation PTW/PP1 Phosphatase Complex Cellular Localization Organelle Transport Along Microtubule Cellular Response To Muramyl Dipeptide
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