PDE4DIP and C19orf66

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE4DIP	C19orf66
Gene Name		phosphodiesterase 4D interacting protein	chromosome 19 open reading frame 66
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	Protein Binding Enzyme Binding
	Biological Process	Cellular Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933)
Protein-Protein Interactions		64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	32 interactors: ADAMTSL4 CADPS CCDC136 DRICH1 DTNBP1 IKZF1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NOTCH2NL PDE4DIP SPRY2 SSX2IP TCF4 TERF1 TNS2 TRAF1
Entrez ID		9659	55337
HPRD ID		10482	07747
Ensembl ID		ENSG00000178104	ENSG00000130813
Uniprot IDs		F8WAP3 Q5VU43	Q9NUL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction	Regulation Of Signal Transduction Developmental Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signaling Cellular Localization Organelle Localization Cellular Component Assembly Negative Regulation Of Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Vesicle Localization Protein Complex Assembly Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Anatomical Structure Development Organelle Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Kinase B Signaling Embryonic Organ Morphogenesis Negative Regulation Of Protein Localization To Nucleus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Organelle Localization Cellular Protein Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Microtubule-based Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Telomeric Loop Formation Age-dependent Telomere Shortening Cell Cycle Establishment Of Localization In Cell Positive Regulation Of Intracellular Signal Transduction Telomere Maintenance Via Telomere Shortening Catecholamine Secretion Maintenance Of DNA Repeat Elements Negative Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Vesicle Transport Multicellular Organism Growth Regulation Of Apoptotic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Kinase B Signaling
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