PDE4DIP and KLC4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE4DIP	KLC4
Gene Name		phosphodiesterase 4D interacting protein	kinesin light chain 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	Protein Binding Enzyme Binding	Microtubule Motor Activity
	Biological Process	Cellular Protein Complex Assembly	Metabolic Process
Pathways			MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933)
Protein-Protein Interactions		64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	17 interactors: ABI3 APP CEP57L1 COIL KATNAL1 KPNA2 KRT13 KRT15 KRT31 MEOX2 NECAB2 PDE4DIP SLC16A9 SYNE4 TADA2A USHBP1 YWHAZ
Entrez ID		9659	89953
HPRD ID		10482	13932
Ensembl ID		ENSG00000178104	ENSG00000137171
Uniprot IDs		F8WAP3 Q5VU43	B4DME9 Q9NSK0
PDB IDs
Enriched GO Terms of Interacting Partners?		Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction
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