PDE4DIP and FAM74A4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PDE4DIP	FAM74A4
Description		phosphodiesterase 4D interacting protein	family with sequence similarity 74 member A4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Microtubule Organizing Center Cytoskeleton Myofibril Cortical Microtubule Plus-end
	Molecular Function	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	Centrosome Cycle Astral Microtubule Organization Protein-containing Complex Assembly Positive Regulation Of Microtubule Nucleation Regulation Of Golgi Organization
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Cutaneous mastocytosis ( 32752121) Macrovascular complications in type 2 diabetes ( 33430853) Mastocytosis ( 32752121)
Interacting Genes		88 interacting genes: ADH1B AEN AIRIM AKTIP ANKRD11 ARNT2 BYSL CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CLIP4 CWF19L2 DSCAM DSCR9 EGR2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RSPH1 RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 TK1 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26	26 interacting genes: CCDC85B CCNDBP1 CEP44 EFEMP2 EMG1 HMBOX1 IKZF1 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LZTS2 MEOX2 MTUS2 NOTCH2NLA PDE4DIP PHC2 RPGRIP1 STX11 TCF4 TMCC2
Entrez ID		9659	401508
HPRD ID		10482	16982
Ensembl ID		ENSG00000178104	ENSG00000293075
Uniprot IDs		A0A075B749 A0A8Q3SI21 A0A8Q3SI83 A0A8Q3WM32 A0A994J5E0 E9PQG4 Q5VU43
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Zinc Ion Binding Nucleus Cytoskeleton Organization Cytoskeleton Protein Binding DNA-binding Transcription Factor Activity	Intermediate Filament Keratin Filament Identical Protein Binding Centrosome
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