ARHGEF6 and PAK1

  • Number of citations of the paper that reports this interaction (PMID 9659915)
  • 169
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

ARHGEF6

PAK1

Gene Name Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 p21 protein (Cdc42/Rac)-activated kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 22 interactors: ADAM15 ARHGEF7 BMPR1B CAPNS1 CDC42 EPHB2 GIT1 GPRASP2 PAK1 PAK2 PAK3 PARVB SH2D1A SH3GL3 SMAD1 SMAD2 SMAD3 TGFBR1 TGFBR2 TMEM108 YWHAG ZNF580 83 interactors: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 C5orf42 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CRIPAK CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 HGS HIST1H3A HIST1H4A HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1F PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SORBS3 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83
Entrez ID 9459 5058
HPRD ID 02226 03995
Ensembl ID ENSG00000129675 ENSG00000149269
Uniprot IDs B7Z3C7 Q15052 Q8N4Q3 B3KNX7 Q13153
PDB IDs 1UJY 1WYR 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acted  analyzing  bioinformatic  constructed  crc  dataset  david  degs  disturbed  downloaded  fzd2  gse23878  hprd  hub  intend  jup  kegg  module  modules  networks  omnibus  pdgfrb  prkcb  student  theses  uncovered  wnt11  wnt2  wnt5a 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Difference) ?
acted  analyzing  bioinformatic  constructed  crc  dataset  david  degs  disturbed  downloaded  fzd2  gse23878  hprd  hub  intend  jup  kegg  module  modules  networks  omnibus  pdgfrb  prkcb  student  theses  uncovered  wnt11  wnt2  wnt5a 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Intersection) ?