PAK1 and BRSK1

  • Number of citations of the paper that reports this interaction (PMID 22669945)
  • 7
  • Data Source:
  • BioGRID (enzymatic study)

PAK1

BRSK1

Gene Name p21 protein (Cdc42/Rac)-activated kinase 1 BR serine/threonine kinase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Menarche and menopause (age at onset) ( 19448621)
  • Menopause (age at onset) ( 19448619)
Protein-Protein Interactions 83 interactors: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 C5orf42 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CRIPAK CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 HGS HIST1H3A HIST1H4A HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1F PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SORBS3 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83 8 interactors: BRCA1 CDC25B CDC25C HSD17B7 HSPA1A PAK1 UBC WEE1
Entrez ID 5058 84446
HPRD ID 03995 12533
Ensembl ID ENSG00000149269 ENSG00000160469
Uniprot IDs B3KNX7 Q13153 Q8TDC3
PDB IDs 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
aicar  ampk  ampkbeta  blunted  brsk2  c433s  caax  cys433  farnesylated  farnesylation  fertile  imidazolecarboxamide  knockin  lkb1  lkb1c433s  lkb1s431a  mark4  mimetic  myristoylation  nuak  nuak1  phenformin  prenylated  raises  riboside  s431a  ser431  sik3  snf1 
Tagcloud (Difference) ?
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
aicar  ampk  ampkbeta  blunted  brsk2  c433s  caax  cys433  farnesylated  farnesylation  fertile  imidazolecarboxamide  knockin  lkb1  lkb1c433s  lkb1s431a  mark4  mimetic  myristoylation  nuak  nuak1  phenformin  prenylated  raises  riboside  s431a  ser431  sik3  snf1 
Tagcloud (Intersection) ?