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DGCR6 and KLHL12
Number of citations of the paper that reports this interaction (PubMedID
24722188
)
69
Data Source:
BioGRID
(two hybrid)
DGCR6
KLHL12
Description
DiGeorge syndrome critical region gene 6
kelch like family member 12
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Extracellular Matrix
Cytoplasm
Cytosol
COPII Vesicle Coat
COPII-coated ER To Golgi Transport Vesicle
Cytoplasmic Vesicle
Cul3-RING Ubiquitin Ligase Complex
Centriolar Satellite
Molecular Function
Protein Binding
Protein Binding
Identical Protein Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
Cell Adhesion
Animal Organ Morphogenesis
Protein Monoubiquitination
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Anatomical Structure Morphogenesis
Tissue Development
Neural Crest Formation
Neural Crest Cell Development
Wnt Signaling Pathway
Vesicle-mediated Transport
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
COPII Vesicle Coating
Pathways
Degradation of DVL
Drugs
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Metabolite levels (
23823483
)
Plasma free amino acid levels (
30659259
)
Plasma free amino acid levels (adjusted for twenty other PFAAs) (
30659259
)
Interacting Genes
67 interacting genes:
ADAMTSL4
AGTRAP
AKAP8L
APP
ARNT2
C1orf94
C3orf62
CBLL1
CBY2
CCDC33
CEP126
CTBP1
DEUP1
DLGAP2
DLX2
DNPEP
DOCK8
EFEMP2
EFHC2
ENKD1
ESS2
FBF1
FH
FTCD
GOLGA2
GSE1
HGS
HOMEZ
IHO1
IKZF3
INIP
KLHL12
KRTAP12-2
LZTS2
MBIP
MEIS2
MEOX2
MIA2
MID2
MIPOL1
NAB2
NECAB2
NOTCH2NLA
NQO2
NUP54
NUP62
PDLIM7
PRDM14
RABGEF1
REL
RFX6
RIMBP3
SPRY2
SS18L1
TCF12
TCF4
TFIP11
TLE5
TRAF1
TRAF2
TRIM27
TUBGCP4
VCP
ZBED1
ZC4H2
ZNF398
ZNF446
58 interacting genes:
ARAF
ATXN1
BAG6
BCL6
C1QTNF2
CARD10
CCBE1
COL8A1
CPSF6
CRTC3
CUL3
DGCR6
DRD4
DVL3
FAM90A1
FBXL17
FGD2
FLNA
GLYCTK
INMT
KEAP1
KLHL2
KLHL24
KLHL3
LNPK
LNX1
MAPRE1
MED25
MED28
MPP1
MRPL10
MTNR1A
MYO15B
NDC80
NTAQ1
PDCD6
PDGFRB
PEA15
PLEKHA4
PNKP
PRR13
RGL3
RIN1
RIT1
RNF4
RPP25L
SDCBP
SNX20
SYNE4
TAOK2
TBC1D10C
TCEANC
TTBK2
UBE2I
VEGFB
VTA1
ZBP1
ZBTB4
Entrez ID
8214
59349
HPRD ID
03177
13925
Ensembl ID
ENSG00000183628
ENSG00000117153
Uniprot IDs
Q14129
X5D7D2
Q53G59
Q9H7R2
PDB IDs
2VPJ
6TTK
6V7O
8OIO
8RBH
Enriched GO Terms of Interacting Partners
?
Identical Protein Binding
Protein Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Neuron Differentiation
PTB Domain Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Microtubule-based Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Ras Protein Signal Transduction
Regulation Of Primary Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Microtubule Cytoskeleton Organization Involved In Mitosis
Positive Regulation Of Macromolecule Metabolic Process
Nuclear Pore Central Transport Channel
Regulation Of Transcription By RNA Polymerase II
Microtubule
Spindle Pole
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Thioesterase Binding
Positive Regulation Of Metabolic Process
DNA Binding
Regulation Of Neuron Differentiation
Chromatin
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of Ras Protein Signal Transduction
Notch Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Cul3-RING Ubiquitin Ligase Complex
Protein Binding
Regulation Of Signal Transduction
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-like Ligase-substrate Adaptor Activity
Identical Protein Binding
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Modification Process
POZ Domain Binding
Proteolysis Involved In Protein Catabolic Process
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Regulation Of Organelle Organization
Regulation Of Cell Communication
Regulation Of Signaling
Actin Cytoskeleton Organization
Positive Regulation Of Signal Transduction
Proteasomal Protein Catabolic Process
Positive Regulation Of Organelle Organization
Cytoskeleton Organization
Actin Filament-based Process
Paraspeckles
Protein K48-linked Ubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Cell Motility
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Motility
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Cellular Component Assembly
Regulation Of Locomotion
Positive Regulation Of Locomotion
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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