DGCR6 and C1orf94

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		DGCR6	C1orf94
Description		DiGeorge syndrome critical region gene 6	chromosome 1 open reading frame 94
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Extracellular Matrix
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Animal Organ Morphogenesis
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)	Generalized epilepsy ( 22949513) Lateral ventricle temporal horn volume ( 31530798) Pediatric nonalcoholic steatohepatitis ( 28918882) Sleep duration (short sleep) ( 30846698)
Interacting Genes		67 interacting genes: ADAMTSL4 AGTRAP AKAP8L APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 ESS2 FBF1 FH FTCD GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 INIP KLHL12 KRTAP12-2 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446	89 interacting genes: ACTN3 AIRIM AKAP9 ATRIP ATXN1 ATXN1L BANP BOLA1 BOLA2 BOLA2B BOLL BYSL CAMK2A CARD9 CCHCR1 CCNJL CDKN2D CFAP206 CHERP CLK1 CRK CRYBA4 DAB1 DAZAP2 DGCR6 DMRTB1 DOK6 DTX2 FAM168A FHL3 GCC1 GORASP2 GRB2 GSE1 HGS HNRNPF HSF2BP INTS11 IPO11 KLHL32 KRTAP6-2 KRTAP7-1 KRTAP8-1 LCE2C LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB NR3C1 OAZ3 OIP5 PITX1 PLA2G10 PLEKHB2 PRKAG1 PROP1 PRR20A PRR20B PRR20C PRR20D PRR20E R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS RFX2 RHOXF2 ROR2 SMAP2 SS18L1 TBX6 TENT5D TLE5 TNPO2 TNS2 TSC1 TXNDC9 UBQLN2 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		8214	84970
HPRD ID		03177	11310
Ensembl ID		ENSG00000183628	ENSG00000142698
Uniprot IDs		Q14129 X5D7D2	Q6P1W5
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Neuron Differentiation PTB Domain Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Microtubule-based Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Ras Protein Signal Transduction Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Macromolecule Metabolic Process Nuclear Pore Central Transport Channel Regulation Of Transcription By RNA Polymerase II Microtubule Spindle Pole Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Thioesterase Binding Positive Regulation Of Metabolic Process DNA Binding Regulation Of Neuron Differentiation Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Ras Protein Signal Transduction Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Protein Binding Identical Protein Binding Iron-sulfur Cluster Assembly Complex Nucleus
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