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DGCR6 and NUP62
Number of citations of the paper that reports this interaction (PubMedID
24722188
)
69
Data Source:
BioGRID
(two hybrid)
DGCR6
NUP62
Description
DiGeorge syndrome critical region gene 6
nucleoporin 62
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Extracellular Matrix
Spindle Pole
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Cytoskeleton
Nuclear Membrane
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
PTB Domain Binding
Hsp90 Protein Binding
Biological Process
Cell Adhesion
Animal Organ Morphogenesis
RNA Export From Nucleus
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Mitotic Metaphase Chromosome Alignment
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Protein Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of DNA-templated Transcription
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
MRNA Transport
Regulation Of Mitotic Spindle Organization
Cellular Senescence
Centriole Assembly
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Metabolite levels (
23823483
)
Plasma free amino acid levels (
30659259
)
Plasma free amino acid levels (adjusted for twenty other PFAAs) (
30659259
)
Interacting Genes
67 interacting genes:
ADAMTSL4
AGTRAP
AKAP8L
APP
ARNT2
C1orf94
C3orf62
CBLL1
CBY2
CCDC33
CEP126
CTBP1
DEUP1
DLGAP2
DLX2
DNPEP
DOCK8
EFEMP2
EFHC2
ENKD1
ESS2
FBF1
FH
FTCD
GOLGA2
GSE1
HGS
HOMEZ
IHO1
IKZF3
INIP
KLHL12
KRTAP12-2
LZTS2
MBIP
MEIS2
MEOX2
MIA2
MID2
MIPOL1
NAB2
NECAB2
NOTCH2NLA
NQO2
NUP54
NUP62
PDLIM7
PRDM14
RABGEF1
REL
RFX6
RIMBP3
SPRY2
SS18L1
TCF12
TCF4
TFIP11
TLE5
TRAF1
TRAF2
TRIM27
TUBGCP4
VCP
ZBED1
ZC4H2
ZNF398
ZNF446
88 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DRC12
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
IDH1
IFT20
IFT25
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NUP153
NUP54
NUP58
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PIN1
PTMA
RANBP2
SMARCA2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
Entrez ID
8214
23636
HPRD ID
03177
05782
Ensembl ID
ENSG00000183628
ENSG00000213024
Uniprot IDs
Q14129
X5D7D2
P37198
PDB IDs
5IJN
5IJO
7PER
7R5J
7R5K
Enriched GO Terms of Interacting Partners
?
Identical Protein Binding
Protein Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Neuron Differentiation
PTB Domain Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Microtubule-based Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Ras Protein Signal Transduction
Regulation Of Primary Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Microtubule Cytoskeleton Organization Involved In Mitosis
Positive Regulation Of Macromolecule Metabolic Process
Nuclear Pore Central Transport Channel
Regulation Of Transcription By RNA Polymerase II
Microtubule
Spindle Pole
Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Thioesterase Binding
Positive Regulation Of Metabolic Process
DNA Binding
Regulation Of Neuron Differentiation
Chromatin
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of Ras Protein Signal Transduction
Notch Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Localization Sequence Binding
Nuclear Pore
NLS-bearing Protein Import Into Nucleus
RNA Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Export
MRNA Transport
Intracellular Transport
Nuclear Import Signal Receptor Activity
Protein Localization To Nucleus
Protein Transport
Establishment Of Protein Localization
Structural Constituent Of Nuclear Pore
Intermediate Filament Organization
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Inclusion Body
Protein Binding
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament-based Process
Intracellular Protein Transport
Cellular Localization
Protein Localization To Organelle
Establishment Of Localization In Cell
Establishment Of Protein Localization To Organelle
Supramolecular Fiber Organization
Nuclear Envelope
Intracellular Protein Localization
Intracellular Transport Of Virus
Keratin Filament
Host Cell
NLS-dependent Protein Nuclear Import Complex
Cytoskeleton Organization
Small GTPase Binding
Intermediate Filament
Protein Export From Nucleus
Keratinization
Nuclear Pore Nuclear Basket
Regulation Of Nucleocytoplasmic Transport
Nuclear Pore Organization
Identical Protein Binding
RNA Export From Nucleus
Nucleus Organization
Organelle Organization
Ribosomal Protein Import Into Nucleus
Viral Penetration Into Host Nucleus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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