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KLHL12 and MPP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KLHL12
MPP1
Gene Name
kelch-like family member 12
membrane protein, palmitoylated 1, 55kDa
Image
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytosol
ER To Golgi Transport Vesicle
Cul3-RING Ubiquitin Ligase Complex
Intracellular
Integral Component Of Plasma Membrane
Membrane
Cortical Cytoskeleton
Stereocilium
Molecular Function
Protein Binding
Guanylate Kinase Activity
Protein Binding
Biological Process
Protein Monoubiquitination
ER To Golgi Vesicle-mediated Transport
Wnt Signaling Pathway
COPII Vesicle Coating
Negative Regulation Of Canonical Wnt Signaling Pathway
Signal Transduction
Nucleotide Phosphorylation
Regulation Of Neutrophil Chemotaxis
Pathways
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
degradation of DVL
Signaling by Wnt
Signaling by WNT in cancer
Drugs
Diseases
GWAS
Hematology traits (
23263863
)
Mean corpuscular volume (
23263863
)
Red blood cell traits (
23446634
)
Protein-Protein Interactions
39 interactors:
ARAF
ATXN1
BAG6
C1QTNF2
CARD10
CCBE1
COL8A1
CPSF6
CUL3
DGCR6
DRD4
DVL3
FGD2
FLNA
GLYCTK
INMT
KLHL2
KLHL3
LNX1
MED28
MPP1
MRPL10
NDC80
PDGFRB
PEF1
PRR13
RIT1
RPP25L
SDCBP
SNX20
SYNE4
TAOK2
TBC1D10C
TTBK2
UBE2I
VEGFB
VTA1
WDYHV1
ZBP1
19 interactors:
AMOTL2
ATP5C1
DNPEP
ERBB2IP
GADD45A
GSK3B
GYPC
HNRNPD
KLHL12
NR1H2
OPTN
RPS6KA1
RPS6KA6
SGSM2
SMN1
STK3
STUB1
TK1
ZAK
Entrez ID
59349
4354
HPRD ID
13925
02370
Ensembl ID
ENSG00000117153
ENSG00000130830
Uniprot IDs
Q53G59
B4E325
Q00013
PDB IDs
2VPJ
2EJY
2EV8
3NEY
Enriched GO Terms of Interacting Partners
?
Regulation Of Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of MAPK Cascade
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Component Assembly
Positive Regulation Of Transferase Activity
Positive Regulation Of Metabolic Process
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Morphogenesis
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Protein Kinase Activity
Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Positive Regulation Of Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Kinase Activity
Coronary Vasculature Development
Actin Cytoskeleton Organization
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Intracellular Signal Transduction
Chromosome Segregation
Actin Filament-based Process
Positive Regulation Of Catalytic Activity
Anatomical Structure Development
Cellular Protein Modification Process
Activation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Ubiquitin-dependent Protein Catabolic Process
Anatomical Structure Formation Involved In Morphogenesis
Modification-dependent Protein Catabolic Process
Cell Projection Assembly
Regulation Of MAP Kinase Activity
Positive Regulation Of Cell Division
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Chemotaxis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Cellular Response To Stress
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Positive Regulation Of Protein Metabolic Process
Regulation Of Signaling
Regulation Of Cellular Protein Metabolic Process
Signal Transduction
Regulation Of MAPK Cascade
Positive Regulation Of Catalytic Activity
Cell Death
Death
Regulation Of Protein Metabolic Process
Positive Regulation Of JNK Cascade
Signaling
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Cell Communication
Regulation Of Catalytic Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Binding
Negative Regulation Of Canonical Wnt Signaling Pathway
Hippo Signaling
Phosphorylation
Intracellular Signal Transduction
Regulation Of JNK Cascade
Positive Regulation Of Cellular Metabolic Process
Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Wnt Signaling Pathway
Positive Regulation Of Protein Modification Process
Cellular Metabolic Process
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Stimulus
Intracellular Transport
Positive Regulation Of Transferase Activity
Positive Regulation Of High-density Lipoprotein Particle Assembly
Positive Regulation Of Secretion Of Lysosomal Enzymes
Positive Regulation Of Pancreatic Juice Secretion
Fetal Process Involved In Parturition
Negative Regulation Of Protein Binding
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Binding
Golgi Vesicle Transport
Positive Regulation Of Cell Death
Positive Regulation Of Protein Serine/threonine Kinase Activity
Wnt Signaling Pathway
Tagcloud
?
boundaries
cdna
conservation
conserved
construction
discs
drosophila
encodes
establish
exon
exons
fugu
gives
heavily
homology
identity
intron
knockout
lethal
likewise
location
notion
p55
palmitoylated
puffer
rubripes
studying
suppressor
ubiquitously
Tagcloud (Difference)
?
boundaries
cdna
conservation
conserved
construction
discs
drosophila
encodes
establish
exon
exons
fugu
gives
heavily
homology
identity
intron
knockout
lethal
likewise
location
notion
p55
palmitoylated
puffer
rubripes
studying
suppressor
ubiquitously
Tagcloud (Intersection)
?