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DGCR6 and HOMEZ
Number of citations of the paper that reports this interaction (PMID
24722188
)
1
Data Source:
BioGRID
(two hybrid)
DGCR6
HOMEZ
Gene Name
DiGeorge syndrome critical region gene 6
homeobox and leucine zipper encoding
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteinaceous Extracellular Matrix
Nucleus
Nucleus
Nucleolus
Cytoplasm
Molecular Function
Molecular_function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Biological Process
Cell Adhesion
Organ Morphogenesis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
61 interactors:
ADAMTSL4
AES
AGTRAP
APP
ARNT2
C1orf94
C3orf62
CBLL1
CCDC33
CCDC36
CCDC67
CTAGE5
CTBP1
DLGAP2
DLX2
DNPEP
DOCK8
EFEMP2
EFHC2
ENKD1
FBF1
GOLGA2
GSE1
HGS
HOMEZ
IKZF3
KIAA1377
KLHL12
LZTS2
MBIP
MEIS2
MEOX2
MID2
MIPOL1
NAB2
NECAB2
NOTCH2NL
NQO2
NUP54
NUP62
PDLIM7
PRDM14
RABGEF1
REL
RFX6
RIMBP3
SPERT
SPRY2
SS18L1
TCF12
TCF4
TFIP11
TRAF1
TRAF2
TRIM27
TUBGCP4
VCP
ZBED1
ZC4H2
ZNF398
ZNF446
31 interactors:
AEN
AES
APITD1
DEF6
DGCR6
DNTTIP1
EBF1
EIF4E2
GRB2
HOXC8
KPNA2
LNX1
LRRC7
MAD2L1BP
MED18
MRPL11
NCK2
PIN1
PRKAA1
PRKAA2
RBM39
RNF8
RPL9
SDCBP
SH3RF2
SMYD1
SNRPB2
SUMO2
TCEB3
TRAF4
ZBTB7A
Entrez ID
8214
57594
HPRD ID
03177
12167
Ensembl ID
ENSG00000183628
ENSG00000215271
Uniprot IDs
Q14129
F8WCA3
Q8IX15
PDB IDs
2ECC
2YS9
Enriched GO Terms of Interacting Partners
?
RNA Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Protein Binding
Regulation Of ERBB Signaling Pathway
Negative Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cell Death
Developmental Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Signal Transduction
Regulation Of Signaling
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Protein Ubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Binding
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Modification By Small Protein Conjugation
Nitrogen Compound Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Response To Ionizing Radiation
RNA Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Regulation Of Energy Homeostasis
Positive Regulation Of Glycolytic Process
Negative Regulation Of Cellular Metabolic Process
Fatty Acid Homeostasis
Biosynthetic Process
Histone-serine Phosphorylation
Positive Regulation Of Metabolic Process
Cellular Response To Glucose Starvation
Regulation Of Glycolytic Process
Regulation Of Cellular Process
Chromatin Modification
Negative Regulation Of TOR Signaling
Protein Modification By Small Protein Conjugation
Regulation Of MAPK Cascade
Histone Exchange
Cholesterol Biosynthetic Process
Insulin Receptor Signaling Pathway
Positive Regulation Of Autophagy
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Cellular Protein Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Histone Phosphorylation
Translational Elongation
Histone Modification
Sterol Biosynthetic Process
Negative Regulation Of Glucosylceramide Biosynthetic Process
Cold Acclimation
Regulation Of RNA Metabolic Process
Anion Homeostasis
Chromatin Remodeling
Tagcloud
?
1rn
antidopaminergic
daao
darpp
dgcr2
drd2
drd3
dtnbp1
evolves
facets
forcefully
g72
gabra1
gabra6
gabrp
gria1
grin1
grm3
merge
mglu2
networking
prodh
rgs4
slc1a2
slc1a6
underpinned
unifying
vulnerablility
zdhhc8
Tagcloud (Difference)
?
1rn
antidopaminergic
daao
darpp
dgcr2
drd2
drd3
dtnbp1
evolves
facets
forcefully
g72
gabra1
gabra6
gabrp
gria1
grin1
grm3
merge
mglu2
networking
prodh
rgs4
slc1a2
slc1a6
underpinned
unifying
vulnerablility
zdhhc8
Tagcloud (Intersection)
?