TRAF3 and TRIM37

TRAF3

TRIM37

Name TNF receptor associated factor 3 tripartite motif containing 37
Structure PDB 1FLK PDB 3LRQ
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
GWAS
  • Adult body size ( 32376654 )
  • Age at first birth ( 34211149 )
  • Age at first sexual intercourse ( 34211149 )
  • Albumin-globulin ratio ( 29403010 )
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 )
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 )
  • Allergic disease (asthma, hay fever or eczema) ( 29083406 )
  • Apolipoprotein A1 levels ( 32203549 )
  • Asthma ( 32296059 )
  • Asthma (childhood onset) ( 30929738 )
  • Body mass index ( 29273807 25673413 )
  • Body size at age 10 ( 32376654 )
  • Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125 )
  • Composite immunoglobulin trait (IgA x IgG/IgM) ( 28628107 )
  • Eczema ( 31361310 )
  • Gallstone disease ( 30692554 )
  • Gastroesophageal reflux disease, peptic ulcer disease and/or corresponding medications and treatment ( 33608531 )
  • HDL cholesterol levels ( 32203549 )
  • Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010 )
  • Lymphocyte count ( 27863252 32888494 )
  • Lymphocyte percentage of white cells ( 27863252 32888494 )
  • Major depressive disorder (MTAG) ( 33479212 )
  • Monocyte count ( 32888494 )
  • Multiple sclerosis ( 24076602 31604244 )
  • Neutrophil percentage of white cells ( 32888494 )
  • Non-albumin protein levels ( 29403010 )
  • Red blood cell count ( 32888494 )
  • Serum total protein levels ( 29403010 )
  • Systemic lupus erythematosus ( 33536424 28714469 )
  • Type 2 diabetes ( 32499647 )
Interacting Genes 86 interacting genes: ABCC1 ALPL APOBEC3C ASCC1 AZI2 BEX3 BIVM C10orf62 CASP3 CCDC13 CCDC184 CD27 CD40 CDC37 CELF2 DAXX EDA2R EDAR EWSR1 FAS GMEB2 GRIN1 GRIN2D HEMGN HNRNPC IFT25 IL15 IP6K3 IRF1 LNX1 LTBR MAP2K1 MAP3K14 MAP3K7 MAVS MFF NEDD4L NTAQ1 NUP62 OTUD5 PDLIM7 PDZD4 PIAS2 POM121 PSMB8 PTPN6 RAD23A RIPK1 RIPPLY1 RNF216 RNF4 RRAS2 SAR1A SHANK3 SRC STK38 TANK TBK1 TDP2 TICAM1 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF19 TNFRSF1A TNFRSF1B TNFRSF4 TNFRSF8 TNFRSF9 TRADD TRAF2 TRAF3IP1 TRAF3IP2 TRAF3IP3 TRAF5 TRIM24 TRIM37 UBE2I USP7 ZBP1 ZBTB49 ZMYND11 ZSCAN4 76 interacting genes: ANKRD11 APEX2 APTX AQP1 ARNT2 AXIN1 BASP1 BYSL CCDC33 CDC20B CDC7 CDK5RAP2 CDKL3 COPB1 CWF19L2 DDX6 DLGAP5 DSCAM DTNB DZIP1L ELOA ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PABPC4 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 SYTL4 TCEANC TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZBTB24 ZMAT2 ZNF329 ZNF417 ZNF587 ZNF655
Entrez ID 7187 4591
HPRD ID 03539 05463
Ensembl ID ENSG00000131323 ENSG00000108395
Uniprot IDs A6NHG8 Q13114 O94972
PDB IDs 1FLK 1FLL 1KZZ 1L0A 1RF3 1ZMS 2ECY 2GKW 8T5P 3LRQ
GO Terms Enriched among Interactors