TRAF3 and RIPK1

  • Number of citations of the paper that reports this interaction (PMID 8612133)
  • 159
  • Data Source:
  • HPRD (in vivo, two hybrid)

TRAF3

RIPK1

Gene Name TNF receptor-associated factor 3 receptor (TNFRSF)-interacting serine-threonine kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain imaging in schizophrenia (interaction) ( 19023125)
Protein-Protein Interactions 55 interactors: ABCC1 ALPL APOBEC3C AZI2 BIRC3 CASP3 CD27 CD40 DAXX EDA2R EDAR EWSR1 FAS GRIN1 GRIN2D IL15 IRF1 LTBR MAP2K1 MAP3K14 NGFRAP1 NUP62 OTUD5 PDLIM7 RIPK1 RRAS2 SAR1A SRC TANK TBK1 TDP2 TICAM1 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF19 TNFRSF1A TNFRSF1B TNFRSF4 TNFRSF8 TNFRSF9 TRADD TRAF2 TRAF3IP1 TRAF3IP2 TRAF3IP3 TRAF5 TRIM37 UBE2I USP7 ZBP1 ZMYND11 45 interactors: BIRC2 BIRC3 CASP8 CCDC50 CDC42BPB CFLAR CRADD EGFR FADD FAS HSP90AA1 IKBKB IKBKG ITCH MAP3K14 MAP3K3 MAP3K8 NFKB1 NUMBL OTUD1 PELI1 PTK2 RIPK3 RNF11 RNF216 SQSTM1 TAX1BP1 TICAM1 TNF TNFAIP3 TNFRSF10A TNFRSF10B TNFRSF1A TRADD TRAF1 TRAF2 TRAF3 TRAF5 TRIM38 TRPC4AP UBE2N USP2 XIAP YOD1 ZFAND5
Entrez ID 7187 8737
HPRD ID 03539 04583
Ensembl ID ENSG00000131323 ENSG00000137275
Uniprot IDs A6NHG8 Q13114 Q13546
PDB IDs 1FLK 1FLL 1KZZ 1L0A 1RF3 1ZMS 2ECY 2GKW 4ITH 4ITI 4ITJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf5  traf6  transduction 
allowed  autocrine  back  deficient  endoplasmic  er  instead  interacting  intrinsic  kills  l929  lineage  lymphotoxin  mlkl  necroptosis  necrosis  opportunities  pathologies  protect  remarkably  repression  rescue  reticulum  ripk3  stress  stressors  switch  tnfr1  unresolved 
Tagcloud (Difference) ?
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  residues  strongly  tail  traf2  traf5  traf6  transduction 
allowed  autocrine  back  deficient  endoplasmic  er  instead  interacting  intrinsic  kills  l929  lineage  lymphotoxin  mlkl  necroptosis  opportunities  pathologies  protect  remarkably  repression  rescue  reticulum  ripk3  stress  stressors  switch  tnfr1  unresolved 
Tagcloud (Intersection) ?
necrosis