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TNFRSF1B and TRIM37
Number of citations of the paper that reports this interaction (PMID
11279055
)
30
Data Source:
BioGRID
(pull down)
TNFRSF1B
TRIM37
Gene Name
tumor necrosis factor receptor superfamily, member 1B
tripartite motif containing 37
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Nucleus
Plasma Membrane
Integral Component Of Membrane
Neuronal Cell Body
Varicosity
Membrane Raft
Perinuclear Region Of Cytoplasm
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Inflammatory Response
Immune Response
Aging
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Inflammatory Response
RNA Destabilization
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Cellular Response To Lipopolysaccharide
Cellular Response To Growth Factor Stimulus
Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Etanercept
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
20 interactors:
ADAM17
BMX
CAV1
CD14
CSNK1A1
FANCD2
HIVEP3
KRT18
LTA
PKN1
STAT1
TDP2
TNF
TRAF1
TRAF2
TRAF3
TRAIP
TRIM37
UBQLN1
ZNF420
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
Entrez ID
7133
4591
HPRD ID
01862
05463
Ensembl ID
ENSG00000028137
ENSG00000108395
Uniprot IDs
P20333
A8K0V9
A8K8U4
F8WEE6
O94972
PDB IDs
1CA9
3ALQ
3LRQ
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Tumor Necrosis Factor-mediated Signaling Pathway
Response To Tumor Necrosis Factor
Cellular Response To Tumor Necrosis Factor
Regulation Of Apoptotic Process
Response To Abiotic Stimulus
Regulation Of Cell Death
Cellular Response To Stimulus
Response To Stress
Signal Transduction
Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus
Signaling
Cell Communication
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytokine Production
Response To Hypoxia
Response To Stimulus
Response To Lipopolysaccharide
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune System Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Molecule Of Bacterial Origin
Intracellular Signal Transduction
Positive Regulation Of Cytokine Production
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Chronic Inflammatory Response
Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Response To Cytokine
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cytokine-mediated Signaling Pathway
Immune System Process
Positive Regulation Of JUN Kinase Activity
Response To Bacterium
Toll-like Receptor 4 Signaling Pathway
Response To Lipid
Regulation Of Innate Immune Response
Regulation Of JUN Kinase Activity
Regulation Of Immunoglobulin Secretion
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of Immune Response
Regulation Of Chronic Inflammatory Response
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
Tagcloud
?
balb
casp3
casp7
casp8
caspase3
closure
d10
d5
d7
dermal
execution
extrinsic
fasr
harvested
healing
innovation
intersect
intrinsic
mechanistically
mucosal
preprogrammed
punch
scarring
therapeutics
tongue
tradd
trp53
wound
wounds
Tagcloud (Difference)
?
balb
casp3
casp7
casp8
caspase3
closure
d10
d5
d7
dermal
execution
extrinsic
fasr
harvested
healing
innovation
intersect
intrinsic
mechanistically
mucosal
preprogrammed
punch
scarring
therapeutics
tongue
tradd
trp53
wound
wounds
Tagcloud (Intersection)
?