TNFRSF1B and ZNF420

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TNFRSF1B	ZNF420
Gene Name		tumor necrosis factor receptor superfamily, member 1B	zinc finger protein 420
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Plasma Membrane Integral Component Of Membrane Neuronal Cell Body Varicosity Membrane Raft Perinuclear Region Of Cytoplasm	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Ubiquitin Protein Ligase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response Immune Response Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Inflammatory Response RNA Destabilization Positive Regulation Of Membrane Protein Ectodomain Proteolysis Cellular Response To Lipopolysaccharide Cellular Response To Growth Factor Stimulus Extrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs		Etanercept
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ADAM17 BMX CAV1 CD14 CSNK1A1 FANCD2 HIVEP3 KRT18 LTA PKN1 STAT1 TDP2 TNF TRAF1 TRAF2 TRAF3 TRAIP TRIM37 UBQLN1 ZNF420	8 interactors: CDC42 CDK2AP1 CYP4V2 CYP51A1 HAX1 SLC1A7 TNFRSF1B TRIM28
Entrez ID		7133	147923
HPRD ID		01862	08122
Ensembl ID		ENSG00000028137	ENSG00000197050
Uniprot IDs		P20333	Q8TAQ5
PDB IDs		1CA9 3ALQ
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Tumor Necrosis Factor-mediated Signaling Pathway Response To Tumor Necrosis Factor Cellular Response To Tumor Necrosis Factor Regulation Of Apoptotic Process Response To Abiotic Stimulus Regulation Of Cell Death Cellular Response To Stimulus Response To Stress Signal Transduction Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Signaling Cell Communication Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cytokine Production Response To Hypoxia Response To Stimulus Response To Lipopolysaccharide Immune Response Regulation Of Immune System Process Positive Regulation Of Immune System Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Bacterial Origin Intracellular Signal Transduction Positive Regulation Of Cytokine Production Cell Surface Receptor Signaling Pathway Positive Regulation Of Chronic Inflammatory Response Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Response To Cytokine TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cytokine-mediated Signaling Pathway Immune System Process Positive Regulation Of JUN Kinase Activity Response To Bacterium Toll-like Receptor 4 Signaling Pathway Response To Lipid Regulation Of Innate Immune Response Regulation Of JUN Kinase Activity Regulation Of Immunoglobulin Secretion Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Immune Response Regulation Of Chronic Inflammatory Response	Regulation Of Intracellular Protein Transport Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Positive Regulation Of Protein Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Demethylation Positive Regulation Of Hair Follicle Cell Proliferation Fatty Acid Omega-oxidation Regulation Of Protein Transport Actin Filament Branching Submandibular Salivary Gland Formation Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Targeting To Mitochondrion Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Protein Phosphorylation Convergent Extension Involved In Axis Elongation Regulation Of Protein Localization Establishment Of Golgi Localization Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Intracellular Transport Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Positive Regulation Of Granulocyte Differentiation Regulation Of Protein Heterodimerization Activity Regulation Of Mitochondrion Degradation Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Protein Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Pseudopodium Assembly Nuclear Migration RNA Destabilization Cardiac Conduction System Development Convergent Extension Positive Regulation Of Membrane Protein Ectodomain Proteolysis Golgi Localization Negative Regulation Of Viral Release From Host Cell
Tagcloud ?		balb casp3 casp7 casp8 caspase3 closure d10 d5 d7 dermal execution extrinsic fasr harvested healing innovation intersect intrinsic mechanistically mucosal preprogrammed punch scarring therapeutics tongue tradd trp53 wound wounds
Tagcloud (Difference) ?		balb casp3 casp7 casp8 caspase3 closure d10 d5 d7 dermal execution extrinsic fasr harvested healing innovation intersect intrinsic mechanistically mucosal preprogrammed punch scarring therapeutics tongue tradd trp53 wound wounds
Tagcloud (Intersection) ?