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TNFRSF1B
Gene Name
tumor necrosis factor receptor superfamily, member 1B
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Nucleus
Plasma Membrane
Integral Component Of Membrane
Neuronal Cell Body
Varicosity
Membrane Raft
Perinuclear Region Of Cytoplasm
Molecular Function
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Inflammatory Response
Immune Response
Aging
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Inflammatory Response
RNA Destabilization
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Cellular Response To Lipopolysaccharide
Cellular Response To Growth Factor Stimulus
Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Etanercept
Diseases
GWAS
Protein-protein Interactions
20 interactors:
ADAM17
BMX
CAV1
CD14
CSNK1A1
FANCD2
HIVEP3
KRT18
LTA
PKN1
STAT1
TDP2
TNF
TRAF1
TRAF2
TRAF3
TRAIP
TRIM37
UBQLN1
ZNF420
Entrez ID
7133
HPRD ID
01862
Ensembl ID
ENSG00000028137
Uniprot IDs
P20333
PDB IDs
1CA9
3ALQ
Enriched GO Terms of Interacting Partners
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Apoptotic Process
Programmed Cell Death
Cell Death
Death
Tumor Necrosis Factor-mediated Signaling Pathway
Response To Tumor Necrosis Factor
Cellular Response To Tumor Necrosis Factor
Regulation Of Apoptotic Process
Response To Abiotic Stimulus
Regulation Of Cell Death
Cellular Response To Stimulus
Response To Stress
Signal Transduction
Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus
Signaling
Cell Communication
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cytokine Production
Response To Hypoxia
Response To Stimulus
Response To Lipopolysaccharide
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune System Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Molecule Of Bacterial Origin
Intracellular Signal Transduction
Positive Regulation Of Cytokine Production
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Chronic Inflammatory Response
Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Response To Cytokine
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cytokine-mediated Signaling Pathway
Immune System Process
Positive Regulation Of JUN Kinase Activity
Response To Bacterium
Toll-like Receptor 4 Signaling Pathway
Response To Lipid
Regulation Of Innate Immune Response
Regulation Of JUN Kinase Activity
Regulation Of Immunoglobulin Secretion
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of Immune Response
Regulation Of Chronic Inflammatory Response
Tagcloud
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balb
casp3
casp7
casp8
caspase3
closure
d10
d5
d7
dermal
execution
extrinsic
fasr
harvested
healing
innovation
intersect
intrinsic
mechanistically
mucosal
preprogrammed
punch
scarring
therapeutics
tongue
tradd
trp53
wound
wounds