TNF and TNFRSF1A

  • Number of citations of the paper that reports this interaction (PMID 14743216)
  • 197
  • Data Source:
  • BioGRID (pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

TNF

TNFRSF1A

Gene Name tumor necrosis factor tumor necrosis factor receptor superfamily, member 1A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
Protein-Protein Interactions 21 interactors: ADAM17 ADAM9 BGN CSF1 DCN FYN IFNG LYN MMP17 NFKBIA PDIK1L POU2F1 PRTN3 RC3H1 RIPK1 TNFAIP3 TNFRSF1A TNFRSF1B TRADD TRAF2 YWHAQ 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1
Entrez ID 7124 7132
HPRD ID 01855 01861
Ensembl ID ENSG00000232810 ENSG00000067182
Uniprot IDs P01375 Q5STB3 J9PH39 P19438
PDB IDs 1A8M 1TNF 2AZ5 2E7A 2TUN 2ZJC 2ZPX 3ALQ 3IT8 3L9J 3WD5 4G3Y 4TSV 5TSW 1EXT 1FT4 1ICH 1NCF 1TNR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aminopurine  ap  catalytically  cooperate  cotreatment  de  elicit  endothelial  exert  gamma  ifn  ikappabbeta  inactive  inducible  involves  kappab  neuronal  normally  novo  pkr  possibility  potentiate  require  stranded  synergistic  synergistically  translocation  ultimately 
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
Tagcloud (Difference) ?
aminopurine  ap  catalytically  cooperate  cotreatment  de  elicit  endothelial  exert  gamma  ifn  ikappabbeta  inactive  inducible  involves  kappab  neuronal  normally  novo  pkr  possibility  potentiate  require  stranded  synergistic  synergistically  translocation  ultimately 
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
Tagcloud (Intersection) ?