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SLPI
Gene Name
secretory leukocyte peptidase inhibitor
Image
Gene Ontology Annotations
Cellular Component
Extracellular Matrix
Extracellular Vesicular Exosome
Molecular Function
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Enzyme Binding
Biological Process
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Protein Binding
Negative Regulation Of Viral Genome Replication
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
CTSB
CTSL
CTSS
ELANE
FAM9B
GRN
KLK3
PLSCR1
PRSS2
SGTA
Entrez ID
6590
HPRD ID
00121
Ensembl ID
ENSG00000124107
Uniprot IDs
P03973
PDB IDs
2Z7F
4DOQ
Enriched GO Terms of Interacting Partners
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Extracellular Matrix Disassembly
Collagen Catabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Extracellular Matrix Organization
Extracellular Structure Organization
Cellular Response To Thyroid Hormone Stimulus
Response To Thyroid Hormone
Defense Response
Positive Regulation Of Innate Immune Response
Regulation Of Innate Immune Response
Positive Regulation Of Immune Response
Acute Inflammatory Response
Proteolysis
Regulation Of Immune Response
Toll-like Receptor Signaling Pathway
Positive Regulation Of Immune System Process
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Immune System Process
Response To Stress
Immune Response
Protein Catabolic Process
Regulation Of Immune System Process
Regulation Of Inflammatory Response
Innate Immune Response
Catabolic Process
Inflammatory Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Immune Response-regulating Signaling Pathway
Positive Regulation Of Inflammatory Response
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Factor XII Activation
Neutrophil Mediated Killing Of Fungus
Basement Membrane Disassembly
Macrophage Apoptotic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Response To Hormone Stimulus
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Response To Organic Substance
Response To Stimulus
Positive Regulation Of Fibrinolysis
Negative Regulation Of Chemokine Biosynthetic Process
Negative Regulation Of Interleukin-8 Biosynthetic Process
Response To Yeast
Phosphatidylserine Biosynthetic Process
Tagcloud
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21x
72x
a2
a2t
annexin
attributed
correlating
embedded
entities
facilitating
formalin
heterotetramer
hnscc
hnsccs
hpv
inverse
lab
nonsmokers
paraffin
protect
protects
putatively
scc
separately
smokers
supports
surplus
tobacco
tonsillar