BARD1 and MDC1

  • Number of citations of the paper that reports this interaction (PMID 12611903)
  • 35
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

BARD1

MDC1

Gene Name BRCA1 associated RING domain 1 mediator of DNA-damage checkpoint 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 107 interactors: ACP1 AKIP1 AP1B1 ASH2L ATP1B1 ATP1B3 BCCIP BCL3 BRCA1 BRD7 BRIP1 CAP1 CASC1 CCDC136 CEP70 CHD3 CNTN4 COL1A1 COMMD1 CRIPAK CSTF1 DCC DDX39B EWSR1 EXOC5 FAM9B FEZ1 FKBP1A FKBP2 FKBP3 FUCA1 GIT1 GOLGA2 GPRASP2 H2AFX HAP1 HIST2H2AC HNRNPC HNRNPLL HSPA14 IDI1 IKBKAP ING5 KAT5 KAT7 KBTBD7 KRT40 LDOC1 LGALS3 LGALS8 LRIF1 MDC1 MRPS22 MSH2 MSH3 MSH6 MT2A ND1 NFKBIA NPC2 OLA1 PCBP2 PDXK PDZD8 PIAS1 PIAS4 POLR2A POLR2H POMZP3 POU2F1 PSMA7 PTN RBBP8 RBMY2BP RPS20 SELENBP1 SETDB1 SMCHD1 SNRNP200 SNX3 SPAG5 SRSF2 TCERG1 TMEM248 TOP1 TP53 TRAF1 TRAPPC11 TRAPPC8 TULP2 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2W UBE3A UBR5 UBXN1 WDR61 XRCC6 ZFP64 ZHX1 ZNF121 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251
Entrez ID 580 9656
HPRD ID 03354 16252
Ensembl ID ENSG00000138376 ENSG00000137337
Uniprot IDs Q99728 A1Z5I9 Q14676
PDB IDs 1JM7 2NTE 2R1Z 3C5R 3FA2 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
10ng  agreed  atr  belonged  biosynthetic  biphenyls  brca2  dioxin  fancd2  figf  hands  immunoblots  impulses  kcnma1  lactational  mycn  ndl  neurobiological  npy4r  ontology  operator6  pcbs  performances  projection  rad51  scn1a  summation  transcriptomic  validating 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Difference) ?
10ng  agreed  atr  belonged  biosynthetic  biphenyls  brca2  dioxin  fancd2  figf  hands  immunoblots  impulses  kcnma1  lactational  mycn  ndl  neurobiological  npy4r  ontology  operator6  pcbs  performances  projection  scn1a  summation  transcriptomic  validating 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Intersection) ?
rad51