BARD1 and ND1

Number of citations of the paper that reports this interaction (PMID 22990118)
7

Data Source:
BioGRID (two hybrid)

		BARD1	ND1
Gene Name		BRCA1 associated RING domain 1	NADH dehydrogenase, subunit 1 (complex I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm BRCA1-BARD1 Complex Intracellular Membrane-bounded Organelle BRCA1-A Complex
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Kinase Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Tissue Homeostasis DNA Repair Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Protein Ubiquitination Negative Regulation Of MRNA 3'-end Processing Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Protein Export From Nucleus Protein K6-linked Ubiquitination
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS		Neuroblastoma ( 22941191 21124317) Neuroblastoma (high-risk) ( 19412175)
Protein-Protein Interactions		107 interactors: ACP1 AKIP1 AP1B1 ASH2L ATP1B1 ATP1B3 BCCIP BCL3 BRCA1 BRD7 BRIP1 CAP1 CASC1 CCDC136 CEP70 CHD3 CNTN4 COL1A1 COMMD1 CRIPAK CSTF1 DCC DDX39B EWSR1 EXOC5 FAM9B FEZ1 FKBP1A FKBP2 FKBP3 FUCA1 GIT1 GOLGA2 GPRASP2 H2AFX HAP1 HIST2H2AC HNRNPC HNRNPLL HSPA14 IDI1 IKBKAP ING5 KAT5 KAT7 KBTBD7 KRT40 LDOC1 LGALS3 LGALS8 LRIF1 MDC1 MRPS22 MSH2 MSH3 MSH6 MT2A ND1 NFKBIA NPC2 OLA1 PCBP2 PDXK PDZD8 PIAS1 PIAS4 POLR2A POLR2H POMZP3 POU2F1 PSMA7 PTN RBBP8 RBMY2BP RPS20 SELENBP1 SETDB1 SMCHD1 SNRNP200 SNX3 SPAG5 SRSF2 TCERG1 TMEM248 TOP1 TP53 TRAF1 TRAPPC11 TRAPPC8 TULP2 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2W UBE3A UBR5 UBXN1 WDR61 XRCC6 ZFP64 ZHX1 ZNF121	10 interactors: BARD1 BRCA1 DHDDS LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 TST
Entrez ID		580	4535
HPRD ID		03354	08365
Ensembl ID		ENSG00000138376
Uniprot IDs		Q99728	P03886 Q85KV6
PDB IDs		1JM7 2NTE 2R1Z 3C5R 3FA2
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair Protein Polyubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Nitrogen Compound Metabolic Process Double-strand Break Repair DNA Metabolic Process Gene Expression Chromosome Organization Regulation Of Metabolic Process Protein K48-linked Ubiquitination Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Protein Ubiquitination Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Response To Stress Cell Cycle Checkpoint DNA Recombination Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Protein Ubiquitination Positive Regulation Of Cellular Metabolic Process Meiotic Mismatch Repair Cellular Macromolecule Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Modification-dependent Protein Catabolic Process Chromatin Organization DNA Damage Checkpoint Cellular Macromolecule Catabolic Process Immune System Process Viral Process Cell Cycle Proteolysis Involved In Cellular Protein Catabolic Process Organelle Organization Cellular Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated	Protein K6-linked Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Histone H3-K4 Methylation Nitrogen Compound Metabolic Process Positive Regulation Of Histone Acetylation Response To Ionizing Radiation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Nucleobase-containing Compound Metabolic Process DNA Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Histone Methylation DNA Recombination Cellular Macromolecule Biosynthetic Process Regulation Of Histone Acetylation Macromolecule Biosynthetic Process Regulation Of Histone Methylation Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Neuron Death Positive Regulation Of Histone Modification Positive Regulation Of Histone H4-K20 Methylation Negative Regulation Of Formation Of Translation Preinitiation Complex Positive Regulation Of Histone H3-K36 Methylation DNA Ligation Involved In DNA Recombination Positive Regulation Of Histone H4-K16 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Viral Transcription DNA Metabolic Process Signal Transduction In Response To DNA Damage Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Response To Radiation Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of MRNA 3'-end Processing Cyanate Catabolic Process Biosynthetic Process Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Protein Localization To Endoplasmic Reticulum Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation RNA Import Into Mitochondrion RRNA Import Into Mitochondrion Viral Process
Tagcloud ?		10ng agreed atr belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	12s 16s 18s coi cys distinction eastern genus honshu japan markers mature met mitochondrial mountainous oka orobdella orobdellamasaakikuroiwai orobdellawhitmani phylogenetic phylogroups quadrannulate rdna relationships reveled sister sp trna val
Tagcloud (Difference) ?		10ng agreed atr belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating	12s 16s 18s coi cys distinction eastern genus honshu japan markers mature met mitochondrial mountainous oka orobdella orobdellamasaakikuroiwai orobdellawhitmani phylogenetic phylogroups quadrannulate rdna relationships reveled sister sp trna val
Tagcloud (Intersection) ?