LTB4R2 and SLC2A1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		LTB4R2	SLC2A1
Description		leukotriene B4 receptor 2	solute carrier family 2 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane	Golgi Membrane Female Germ Cell Nucleus Photoreceptor Inner Segment Female Pronucleus Cytoplasm Cytosol Plasma Membrane Caveola Cell-cell Junction Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Vesicle Sarcolemma Melanosome Membrane Raft Synapse Extracellular Exosome Blood Microparticle Presynapse Glucose Transporter Complex
	Molecular Function	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding Fucose Transmembrane Transporter Activity Kinase Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway	Response To Hypoxia Central Nervous System Development Female Pregnancy Fucose Transmembrane Transport Long-chain Fatty Acid Import Across Plasma Membrane L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Photoreceptor Cell Maintenance D-glucose Import Transmembrane Transport Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response D-glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier Response To Thyroglobulin Triiodothyronine D-glucose Transmembrane Transport
Pathways		Leukotriene receptors G alpha (q) signalling events	Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis
Drugs		Amelubant Leukotriene B4	Resveratrol Carboxymethylcellulose
Diseases			GLUT1 deficiency syndrome (GLUT1DS); Glucose transport defect of the blood-brain barrier Primary torsion dystonia (PTD)
GWAS		Anorectal malformation ( 31136621) Height ( 28552196)	Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pre-treatment viral load in HIV-1 infection ( 31219150) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) White blood cell count ( 32888494)
Interacting Genes		46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B	18 interacting genes: CALR CANX CCR2 COPS6 GAPDH GIPC1 GPR35 HSPB2 LTB4R2 PDIA3 PTK2B STOM SUMO1 TXNIP UBE2I USP2 VHL WWP1
Entrez ID		56413	6513
HPRD ID		16153	00683
Ensembl ID		ENSG00000213906	ENSG00000117394
Uniprot IDs		B4E292 Q9NPC1	P11166 Q59GX2
PDB IDs			4PYP 5EQG 5EQH 5EQI 6THA
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B	Protein Folding In Endoplasmic Reticulum Perinuclear Region Of Cytoplasm Modulation Of Chemical Synaptic Transmission Regulation Of Protein Stability Small Protein Activating Enzyme Binding Protein Stabilization MHC Class I Peptide Loading Complex Peptide Antigen Assembly With MHC Class I Protein Complex Negative Regulation Of Catalytic Activity Protein Modification Process Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Cell Communication Regulation Of Cell Communication Glutamatergic Synapse Regulation Of Signaling Chemokine-mediated Signaling Pathway Cellular Response To Interleukin-7 Response To Interleukin-7 Post-translational Protein Modification Protein Folding Positive Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Transcription Factor Binding Positive Regulation Of Signal Transduction Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Monoatomic Ion Transport Chemokine Receptor Activity Protein Modification By Small Protein Conjugation Endoplasmic Reticulum Quality Control Compartment Negative Regulation Of RNA Biosynthetic Process Regulation Of Lymphocyte Chemotaxis Unfolded Protein Binding Negative Regulation Of Transporter Activity Protein Metabolic Process Presynaptic Cytosol Peptide Binding Postsynaptic Cytosol Lumenal Side Of Endoplasmic Reticulum Membrane Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Potassium Ion Transport Negative Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Regulation Of Biological Quality Positive Regulation Of Signaling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Synaptic Transmission, Glutamatergic
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?