SLC2A1

Gene Name		solute carrier family 2 (facilitated glucose transporter), member 1
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Gene Ontology Annotations	Cellular Component	Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Cell-cell Junction Membrane Basolateral Plasma Membrane Midbody Cortical Actin Cytoskeleton Melanosome Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transporter Activity Identical Protein Binding Xenobiotic Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity
	Biological Process	Carbohydrate Metabolic Process Energy Reserve Metabolic Process Protein Complex Assembly Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Response To Osmotic Stress Hexose Transport Pathogenesis Glucose Transport L-ascorbic Acid Metabolic Process Cellular Response To Glucose Starvation Xenobiotic Transport Small Molecule Metabolic Process Regulation Of Insulin Secretion Transmembrane Transport Dehydroascorbic Acid Transport
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Integration of energy metabolism Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG SLC-mediated transmembrane transport Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective AMN causes hereditary megaloblastic anemia 1 Myoclonic epilepsy of Lafora Glycogen storage diseases Defects in cobalamin (B12) metabolism Defective GIF causes intrinsic factor deficiency Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Regulation of insulin secretion Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Vitamin C (ascorbate) metabolism Hexose transport Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Metabolism of water-soluble vitamins and cofactors Defective MUT causes methylmalonic aciduria mut type Defects in biotin (Btn) metabolism Metabolism of carbohydrates Glucose transport Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-protein Interactions		11 interactors: CALR CANX COPS6 GAPDH GIPC1 PDIA3 PTK2B STOM SUMO1 UBE2I VHL
Entrez ID		6513
HPRD ID		00683
Ensembl ID		ENSG00000117394
Uniprot IDs		P11166 Q59GX2
PDB IDs		1SUK
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Peptidyl-amino Acid Modification Regulation Of Protein Stability Cellular Protein Modification Process Posttranscriptional Regulation Of Gene Expression Protein Stabilization Cellular Protein Metabolic Process Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Localization To Nucleus Protein Sumoylation Response To Lithium Ion Protein Metabolic Process Antigen Processing And Presentation Of Peptide Antigen Negative Regulation Of Cellular Metabolic Process Immune System Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Translation Protein Folding Antigen Processing And Presentation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chaperone-mediated Protein Folding Protein Glycosylation Macromolecule Glycosylation Positive Regulation Of Leukocyte Chemotaxis Glycosylation Peptide Antigen Assembly With MHC Class I Protein Complex Peptidyl-cysteine S-trans-nitrosylation Positive Regulation Of SUMO Transferase Activity Regulation Of Acid-sensing Ion Channel Activity Endothelial Cell Migration Regulation Of Protein Catabolic Process Glycoprotein Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Leukocyte Migration Negative Regulation Of Translation Epithelial Cell Migration Epithelium Migration Carbohydrate Metabolic Process Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis Glycoprotein Metabolic Process Protein Localization Positive Regulation Of Chemotaxis Negative Regulation Of Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Tagcloud ?		atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc37a4 washings