LTB4R2 and TMED1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		LTB4R2	TMED1
Description		leukotriene B4 receptor 2	transmembrane p24 trafficking protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway	Immune System Process Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Signal Transduction Cell-cell Signaling Protein Transport Innate Immune Response
Pathways		Leukotriene receptors G alpha (q) signalling events
Drugs		Amelubant Leukotriene B4
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B	6 interacting genes: F2RL1 GPR37 IL1RL1 LTB4R2 SEC23B SMAD3
Entrez ID		56413	11018
HPRD ID		16153	05653
Ensembl ID		ENSG00000213906	ENSG00000099203
Uniprot IDs		B4E292 Q9NPC1	Q13445
PDB IDs			7RRM
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B	Positive Regulation Of Positive Chemotaxis Proteinase-activated Receptor Activity Positive Regulation Of Interleukin-1 Production Positive Regulation Of Chemokine Production Positive Regulation Of Cytokine Production Regulation Of Chemokine Production Regulation Of Interleukin-1 Production Regulation Of Type II Interferon Production Positive Regulation Of Glomerular Filtration Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium G Protein-coupled Receptor Activity Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Regulation Of Interleukin-1 Beta Production Neuropeptide Signaling Pathway Prosaposin Receptor Activity G Protein-coupled Peptide Receptor Activity Sterol Response Element Binding Positive Regulation Of Transforming Growth Factor Beta3 Production Ameboidal-type Cell Migration Paraxial Mesoderm Morphogenesis Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Interleukin-33 Binding Interleukin-33 Receptor Activity Leukotriene B4 Receptor Activity Leukotriene Receptor Activity Regulation Of Wound Healing Positive Regulation Of Chemotaxis Myeloid Leukocyte Differentiation Positive Regulation Of Killing Of Cells Of Another Organism Regulation Of Lung Blood Pressure Leukotriene Signaling Pathway Cell-cell Junction Organization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Cytoskeleton Organization Mature Conventional Dendritic Cell Differentiation Regulation Of Neutrophil Mediated Cytotoxicity Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Signal Transduction Regulation Of Response To Wounding Regulation Of Blood Pressure Thrombin-activated Receptor Activity Positive Regulation Of Dopamine Metabolic Process Pericardium Development Mesoderm Morphogenesis
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