LTB4R2 and RPN2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		LTB4R2	RPN2
Description		leukotriene B4 receptor 2	ribophorin II
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Nuclear Body Oligosaccharyltransferase Complex A Oligosaccharyltransferase Complex B
	Molecular Function	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding
	Biological Process	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway	Protein Glycosylation Protein N-linked Glycosylation Protein Modification Process
Pathways		Leukotriene receptors G alpha (q) signalling events	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs		Amelubant Leukotriene B4
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196)	Appendicular lean mass ( 33097823) Height ( 31562340) Hippocampal atrophy ( 19668339) Initial pursuit acceleration in psychotic disorders ( 29064472) Kawasaki disease ( 33692975)
Interacting Genes		46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B	17 interacting genes: ADRM1 BCL2L13 EZH2 FBN3 ISG15 LINC00632 LTB4R2 NDRG1 NGFR PDE4B PTEN RBBP4 RCHY1 RHOA SLC22A2 SMO WEE2-AS1
Entrez ID		56413	6185
HPRD ID		16153	01609
Ensembl ID		ENSG00000213906	ENSG00000118705
Uniprot IDs		B4E292 Q9NPC1	P04844
PDB IDs			6S7O 6S7T 8B6L 8PN9
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B	Dendritic Spine Negative Regulation Of Hair Follicle Development Regulation Of Protein Modification Process Negative Regulation Of Cell Size Forebrain Morphogenesis ESC/E(Z) Complex Myelin Maintenance Odontogenesis Negative Regulation Of Cell Migration Animal Organ Development Regulation Of Cell Migration Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Negative Regulation Of Cell Motility Regulation Of Cell Motility Negative Regulation Of Cell Communication Regulation Of Hair Cycle Regulation Of Hair Follicle Development Dentate Gyrus Development Negative Regulation Of Locomotion Regulation Of Locomotion Central Nervous System Development Hair Follicle Morphogenesis Molecular Function Inhibitor Activity Regulation Of Protein Phosphorylation Gamma-tubulin Binding Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process Regulation Of Kidney Development Negative Regulation Of Multicellular Organismal Process Regulation Of Phosphorylation Regulation Of Cell Development Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation Hepatocyte Homeostasis Homeostasis Of Number Of Cells Hair Follicle Development Negative Regulation Of Synaptic Vesicle Clustering Mesenchymal To Epithelial Transition Involved In Metanephric Renal Vesicle Formation Ventral Midline Determination Negative Regulation Of Epithelial Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process Apoptotic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Phosphorus Metabolic Process Rho Protein Signal Transduction Cellular Response To Oxygen-containing Compound Negative Regulation Of Cell-substrate Adhesion Aortic Valve Formation Regulation Of Focal Adhesion Assembly
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