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PRPF40A and WAS
Number of citations of the paper that reports this interaction (PMID
16055720
)
52
Data Source:
BioGRID
(pull down)
PRPF40A
WAS
Gene Name
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
Wiskott-Aldrich syndrome
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Membrane
Nuclear Matrix
Nuclear Speck
Cytosol
Cell-cell Junction
Vesicle Membrane
Actin Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Poly(A) RNA Binding
Proline-rich Region Binding
Actin Binding
Small GTPase Regulator Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Identical Protein Binding
Phospholipase Binding
Biological Process
MRNA Processing
Cytoskeleton Organization
Cell Cycle
Regulation Of Cell Shape
RNA Splicing
Cell Migration
Regulation Of Cytokinesis
Cell Division
Protein Complex Assembly
Defense Response
Immune Response
Blood Coagulation
Actin Polymerization Or Depolymerization
Epidermis Development
Endosomal Transport
Actin Filament Polymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
T Cell Activation
Innate Immune Response
Regulation Of Catalytic Activity
T Cell Receptor Signaling Pathway
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
TCR signaling
Generation of second messenger molecules
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
120 interactors:
ABI1
AKAP8L
APBB1IP
ARFGEF2
ASXL2
ATAD3A
BAG6
BRD4
CAP2
CCT2
CCT4
CCT7
CDK12
CDK13
CHD3
CHERP
CPSF6
CSNK2A1
CUL1
CYFIP1
CYFIP2
DAAM1
DDX46
DHX15
DHX8
DHX9
DIAPH1
ENAH
ERG
EVL
FASLG
FMN1
FMNL1
FMNL2
FMNL3
FN1
FNBP4
FRA10AC1
GAPDH
HIPK1
HNRNPF
HNRNPK
HNRNPU
HNRNPUL1
HSPG2
HTT
IL1RAP
KMT2B
LARP7
LTBP3
MAP1LC3A
MECP2
MMP11
NCKAP1L
NKAP
NONO
PCBP2
PDCD7
PECAM1
PFKL
PIAS1
PIAS3
PIAS4
PPIG
PRKAR1A
PSG5
PTPRF
RBM39
RBMX2
RCC2
RLF
RPL4
RPLP0
SDCBP
SDCBP2
SDK1
SERPINB9
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SMAD4
SNIP1
SNRNP70
SON
SRPK2
STIM2
U2AF1
U2AF2
U2SURP
UBE2I
UBE2K
UBQLN1
UBQLN2
UBQLN4
UBR4
VASP
VCL
WAS
WASF2
WASL
WBP11
WBP4
WBP5
WIPF1
XRCC6
YBX1
YLPM1
YWHAG
ZCCHC10
ZCCHC8
ZFHX3
ZHX1
ZNF341
ZNF451
53 interactors:
ABI3
ACTC1
APBB1
APPBP2
ARHGAP1
ARHGEF7
ARPC1B
ARPC2
ARPC3
BAIAP2L1
BTK
C5AR1
CDC42
CIB1
CRKL
CSNK2A1
CSNK2A2
DLG1
ENAH
EVL
FCHSD2
FGR
FYB
FYN
GAS7
GRB2
HCK
HCLS1
ITK
ITSN2
LCK
LCP2
NCK1
NCK2
NCKIPSD
PIK3R1
PLCG1
PRPF40A
PSTPIP1
PTPN12
RAC1
RGS14
RHOJ
SORBS2
SRC
TCERG1
TEC
TNK2
TRIP10
VASP
WBP4
WIPF1
WIPF2
Entrez ID
55660
7454
HPRD ID
10995
02314
Ensembl ID
ENSG00000196504
ENSG00000015285
Uniprot IDs
O75400
Q05C41
P42768
PDB IDs
1UZC
1YWI
1YWJ
1ZR7
2CQN
2DYF
2KZG
2L5F
2L9V
2LKS
1CEE
1EJ5
1T84
2A3Z
2K42
2OT0
Enriched GO Terms of Interacting Partners
?
RNA Splicing
RNA Processing
MRNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Process
Cellular Metabolic Process
Cellular Component Assembly
Actin Cytoskeleton Organization
MRNA 3'-splice Site Recognition
Actin Polymerization Or Depolymerization
Actin Filament-based Process
Cytoskeleton Organization
RNA Biosynthetic Process
Regulation Of Organelle Organization
Transcription, DNA-templated
Organelle Organization
Regulation Of Metabolic Process
Regulation Of Cellular Process
Regulation Of Cellular Component Organization
CRD-mediated MRNA Stabilization
Regulation Of Gene Expression
Positive Regulation Of Organelle Organization
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Actin Nucleation
Regulation Of Protein Metabolic Process
Protein Sumoylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of RNA Splicing
Cell Differentiation
Negative Regulation Of Cellular Metabolic Process
Actin Filament Organization
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Multicellular Organismal Development
Spliceosomal Complex Assembly
Regulation Of Nitrogen Compound Metabolic Process
Rhythmic Process
Regulation Of RNA Metabolic Process
Developmental Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Immune System Process
Locomotion
Axon Guidance
Regulation Of Immune Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune System Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Filament Organization
Innate Immune Response
Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Axonogenesis
Neuron Projection Morphogenesis
Immune Response
Positive Regulation Of Protein Polymerization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Development
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Neuron Differentiation
Phagocytosis
Positive Regulation Of Protein Complex Assembly
Cell Morphogenesis Involved In Differentiation
Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament Polymerization
Cell Surface Receptor Signaling Pathway
Endocytosis
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Length
Neuron Projection Development
Regulation Of Cellular Component Organization
Antigen Receptor-mediated Signaling Pathway
Cell Projection Morphogenesis
Cell Part Morphogenesis
Response To External Stimulus
Signal Transduction
T Cell Receptor Signaling Pathway
Signaling
Tagcloud
?
arginine
arid3b
arnt2
ascribed
aspartate
catabolism
clmn
defining
deregulated
ectopic
fads1
focusing
fth1
kpna2
lphn2
missense
pard6b
pde4c
pias2
proline
pygl
regardless
repressor
reprogramming
rhobtb2
seq
transcriptome
verifying
xenobiotic
Tagcloud (Difference)
?
arginine
arid3b
arnt2
ascribed
aspartate
catabolism
clmn
defining
deregulated
ectopic
fads1
focusing
fth1
kpna2
lphn2
missense
pard6b
pde4c
pias2
proline
pygl
regardless
repressor
reprogramming
rhobtb2
seq
transcriptome
verifying
xenobiotic
Tagcloud (Intersection)
?