PRPF40A and DZIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRPF40A	DZIP1
Description		pre-mRNA processing factor 40A	DAZ interacting zinc finger protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Membrane Nuclear Matrix Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Centriolar Satellite Ciliary Basal Body Cell Projection Ciliary Transition Fiber Ciliary Base
	Molecular Function	RNA Binding Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity BBSome Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Cytoskeleton Organization Regulation Of Cell Shape RNA Splicing Cell Migration Regulation Of Cytokinesis MRNA Cis Splicing, Via Spliceosome Cell Division	Smoothened Signaling Pathway Germ Cell Development Spermatogenesis Heart Development Cell Projection Organization Cell Differentiation Ciliary Basal Body Organization Protein Localization To Organelle Cilium Organization Establishment Of Protein Localization Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Cilium Assembly Protein Localization To Cilium Sperm Flagellum Assembly Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Protein Localization To Cilium
Pathways		mRNA Splicing - Major Pathway	Hedgehog 'on' state
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Memory dysfunction in frontotemporal lobe dementia ( 29724592) Metabolite levels ( 23823483) Pulse pressure ( 30224653) Refractive error ( 32231278)	Glomerular filtration rate (cystatin C) ( 26831199) Response to statins (LDL cholesterol change) ( 25350695)
Interacting Genes		132 interacting genes: ABI1 AKAP8L APBB1IP ARFGEF2 ASXL2 ATAD3A BAG6 BEND7 BRD4 CAP2 CCNL1 CCT2 CCT4 CCT7 CDK12 CDK13 CHD3 CHERP CPSF6 CT45A1 CUL1 CYFIP1 CYFIP2 DAAM1 DDIT4L DHX15 DHX8 DHX9 DIAPH1 DZIP1 DZIP1L ENAH ERG EVL FASLG FMN1 FMNL1 FMNL2 FMNL3 FN1 FNBP4 FRA10AC1 GAPDH HIPK1 HNRNPF HNRNPK HNRNPU HNRNPUL1 HSPB1 HSPG2 HTT IL1RAP KMT2B LARP7 LTBP3 MAP1LC3A MECP2 MMP11 NCKAP1L NKAP NKAPD1 NONO PCBP2 PDCD7 PECAM1 PFKL PIAS1 PIAS3 PIAS4 PICK1 PPIG PRKAR1A PSG5 PTBP1 PTPRF RBM39 RBMX2 RCC2 RLF RNF10 RPL4 RPLP0 SDCBP SDCBP2 SDK1 SERPINB9 SF1 SF3A1 SF3A2 SF3A3 SF3B2 SF3B3 SFPQ SMAD4 SNIP1 SNRNP70 SON SPMIP2 SREK1 SREK1IP1 SRPK2 STIM2 TCEAL9 TMEM132D U2AF1 U2AF2 U2SURP UBE2I UBE2K UBQLN1 UBQLN2 UBQLN4 UBR4 USP7 VASP VCL WAS WASF2 WASL WBP11 WBP4 WIPF1 XRCC6 YBX1 YLPM1 YWHAG ZCCHC10 ZCCHC8 ZFHX3 ZHX1 ZNF341 ZNF451	12 interacting genes: DAZ1 DAZ4 LUC7L2 MECOM MOS OPTN PPP1R18 PPP2R5A PRPF40A RNF10 TIAM1 TNS2
Entrez ID		55660	22873
HPRD ID		10995	16363
Ensembl ID		ENSG00000196504	ENSG00000134874
Uniprot IDs		A0A7N4I394 A0A8Q3SIG7 A0A8V8TM61 F5H578 O75400	B3KSP1 Q86YF9
PDB IDs		1UZC 1YWI 1YWJ 1ZR7 2CQN 2DYF 2KZG 2L5F 2L9V 2LKS 8PXW 8PXX
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Nuclear Speck Nucleic Acid Binding Spliceosomal Complex Nucleoplasm Nucleus Spliceosomal Complex Assembly RNA Metabolic Process U2 SnRNP Catalytic Step 2 Spliceosome Nucleic Acid Metabolic Process U2-type Prespliceosome Assembly Actin Binding U2-type Precatalytic Spliceosome Profilin Binding SCAR Complex Cellular Component Assembly Actin Polymerization Or Depolymerization Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Ribonucleoprotein Complex MRNA 3'-splice Site Recognition Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Protein-RNA Complex Assembly Actin Filament-based Process Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Metabolic Process Protein Binding Alternative MRNA Splicing, Via Spliceosome U12-type Spliceosomal Complex Regulation Of Macromolecule Metabolic Process PML Body SUMO Ligase Activity Cytosol U2-type Spliceosomal Complex Positive Regulation Of Macromolecule Metabolic Process Actin Cytoskeleton Organization Focal Adhesion Regulation Of Metabolic Process U2-type Prespliceosome CRD-mediated MRNA Stability Complex	Translation Activator Activity 3'-UTR-mediated MRNA Stabilization Kinase Binding U2-type Prespliceosome U1 SnRNP
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