PRPF40A and RCC2

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		PRPF40A	RCC2
Gene Name		PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	regulator of chromosome condensation 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Nuclear Matrix Nuclear Speck	Nucleolus Cytosol Microtubule Midbody Chromosome, Centromeric Core Domain Mitotic Spindle Midzone
	Molecular Function	Protein Binding Poly(A) RNA Binding Proline-rich Region Binding	Protein Binding Microtubule Binding Poly(A) RNA Binding Rac GTPase Binding
	Biological Process	MRNA Processing Cytoskeleton Organization Cell Cycle Regulation Of Cell Shape RNA Splicing Cell Migration Regulation Of Cytokinesis Cell Division	Mitotic Cell Cycle Endosome Organization Mitotic Nuclear Division Integrin-mediated Signaling Pathway Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Migration Negative Regulation Of GTPase Activity Focal Adhesion Assembly Cell Division Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Chromosome Passenger Complex Localization To Kinetochore Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Basal cell carcinoma ( 18849993)
Protein-Protein Interactions		120 interactors: ABI1 AKAP8L APBB1IP ARFGEF2 ASXL2 ATAD3A BAG6 BRD4 CAP2 CCT2 CCT4 CCT7 CDK12 CDK13 CHD3 CHERP CPSF6 CSNK2A1 CUL1 CYFIP1 CYFIP2 DAAM1 DDX46 DHX15 DHX8 DHX9 DIAPH1 ENAH ERG EVL FASLG FMN1 FMNL1 FMNL2 FMNL3 FN1 FNBP4 FRA10AC1 GAPDH HIPK1 HNRNPF HNRNPK HNRNPU HNRNPUL1 HSPG2 HTT IL1RAP KMT2B LARP7 LTBP3 MAP1LC3A MECP2 MMP11 NCKAP1L NKAP NONO PCBP2 PDCD7 PECAM1 PFKL PIAS1 PIAS3 PIAS4 PPIG PRKAR1A PSG5 PTPRF RBM39 RBMX2 RCC2 RLF RPL4 RPLP0 SDCBP SDCBP2 SDK1 SERPINB9 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SMAD4 SNIP1 SNRNP70 SON SRPK2 STIM2 U2AF1 U2AF2 U2SURP UBE2I UBE2K UBQLN1 UBQLN2 UBQLN4 UBR4 VASP VCL WAS WASF2 WASL WBP11 WBP4 WBP5 WIPF1 XRCC6 YBX1 YLPM1 YWHAG ZCCHC10 ZCCHC8 ZFHX3 ZHX1 ZNF341 ZNF451	3 interactors: ERG PRPF40A RAC1
Entrez ID		55660	55920
HPRD ID		10995	18171
Ensembl ID		ENSG00000196504	ENSG00000179051
Uniprot IDs		O75400 Q05C41	Q9P258
PDB IDs		1UZC 1YWI 1YWJ 1ZR7 2CQN 2DYF 2KZG 2L5F 2L9V 2LKS
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Process Cellular Metabolic Process Cellular Component Assembly Actin Cytoskeleton Organization MRNA 3'-splice Site Recognition Actin Polymerization Or Depolymerization Actin Filament-based Process Cytoskeleton Organization RNA Biosynthetic Process Regulation Of Organelle Organization Transcription, DNA-templated Organelle Organization Regulation Of Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Component Organization CRD-mediated MRNA Stabilization Regulation Of Gene Expression Positive Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Protein Metabolic Process Protein Sumoylation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of RNA Splicing Cell Differentiation Negative Regulation Of Cellular Metabolic Process Actin Filament Organization Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Multicellular Organismal Development Spliceosomal Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of RNA Metabolic Process Developmental Process	Negative Regulation Of Potassium Ion Export Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Regulation Of Heart Rate By Hormone Engulfment Of Apoptotic Cell Mast Cell Chemotaxis Negative Regulation Of Transport Regulation Of Actin Filament-based Process Tangential Migration From The Subventricular Zone To The Olfactory Bulb Olfactory Bulb Interneuron Development Regulation Of Heart Rate By Chemical Signal Regulation Of Cell Morphogenesis Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Peptidyl-histidine Phosphorylation Regulation Of Hydrogen Peroxide Metabolic Process Potassium Ion Export Regulation Of Respiratory Burst Auditory Receptor Cell Morphogenesis Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Phagocytosis, Engulfment Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Olfactory Bulb Interneuron Differentiation Positive Regulation Of Lamellipodium Assembly Phosphorelay Signal Transduction System Positive Regulation Of Potassium Ion Transmembrane Transport Auditory Receptor Cell Development Dopaminergic Neuron Differentiation Membrane Invagination Positive Regulation Of Lamellipodium Organization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Cellular Component Movement Wnt Signaling Pathway, Planar Cell Polarity Pathway Anatomical Structure Arrangement Cell Proliferation Regulation Of Membrane Repolarization Ruffle Assembly Negative Regulation Of Potassium Ion Transport Regulation Of Heart Rate By Cardiac Conduction Hyperosmotic Response Positive Regulation Of Neutrophil Chemotaxis Regulation Of Lamellipodium Assembly Positive Regulation Of Focal Adhesion Assembly Regulation Of Defense Response To Virus By Virus Positive Regulation Of Adherens Junction Organization Cochlea Morphogenesis Positive Regulation Of Granulocyte Chemotaxis
Tagcloud ?		arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic	29c actually advantage agar ascertain brdu carcinoma cdk6 confer downregulated downregulation gastric harbored incorporation microarray mir mirna mkn45 mkn7 mkn74 partly ppic s10 sirnas suppression suppressive transfected utr verified
Tagcloud (Difference) ?		arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic	29c actually advantage agar ascertain brdu carcinoma cdk6 confer downregulated downregulation gastric harbored incorporation microarray mir mirna mkn45 mkn7 mkn74 partly ppic s10 sirnas suppression suppressive transfected utr verified
Tagcloud (Intersection) ?