FBXW7 and CUL1

  • Number of citations of the paper that reports this interaction (PMID 14603323)
  • 106
  • Data Source:
  • HPRD (in vitro)

FBXW7

CUL1

Gene Name F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase cullin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ARL6IP1 CCNE1 CCNE2 CDC34 CREB3L1 CREB3L2 CUL1 EBNA1BP2 FAM101A GLMN GNB2L1 HEY1 HIPK2 JUN KIAA1875 KLF5 LINGO1 MCL1 MED13 MED13L MMS22L MYB MYC NOTCH1 NOTCH4 PARK2 PPARGC1A PSEN1 SHPRH SKP1 STOML1 SUMF2 UBE2D1 55 interactors: ARIH1 BTRC CAND1 CDC34 CDCA3 CDK9 CDKN1B CENPE CHEK1 CHUK CKS1B COMMD1 COPS2 COPS5 COPS6 COPS7A COPS8 DCUN1D4 E2F1 FBXO18 FBXO25 FBXW11 FBXW2 FBXW4 FBXW7 GLMN GPS1 HIPK2 NEDD8 NFKBIA NFKBIB NFKBIE NLK NR1D2 PARK2 PPP1CA PRPF40A PSMB4 PSMD4 PTTG1 RAC2 RANBP2 RBX1 RICTOR RNF7 SENP8 SKP1 SKP2 SMAD3 THRA TRIM21 UBE2E3 UBE2F UBE2M ZC3HC1
Entrez ID 55294 8454
HPRD ID 05888 04389
Ensembl ID ENSG00000109670 ENSG00000055130
Uniprot IDs B7Z2C8 G0Z2K0 Q969H0 S4R3U4 B3KTW0 Q13616
PDB IDs 2OVP 2OVQ 2OVR 1LDJ 1LDK 1U6G 3RTR 3TDU 3TDZ 4F52
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  mitotic  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
Tagcloud (Difference) ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  mitotic  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
Tagcloud (Intersection) ?