Description |
F-box and WD repeat domain containing 7 |
notch receptor 4 |
Image |
|
|
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
|
- A body shape index ( 34021172)
- Age-related macular degeneration ( 22694956)
- Aspartate aminotransferase levels ( 29403010)
- Asthma ( 21804548 31619474)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Bipolar disorder ( 31043756)
- Blood protein levels in cardiovascular risk ( 28369058)
- Chronic hepatitis B infection ( 25802187)
- Circulating myeloperoxidase levels (serum) ( 23620142)
- Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
- Colorectal cancer ( 30529582)
- Crohn's disease ( 23266558)
- Epstein-Barr virus immune response (EBNA-1) ( 23326239)
- Femur bone mineral density x serum urate levels interaction ( 34046847)
- Food antigen IgG levels ( 24962563)
- Hematocrit ( 32888494)
- Hemoglobin ( 32888494)
- High light scatter reticulocyte count ( 32888494)
- Hip circumference adjusted for BMI ( 34021172)
- HIV-1 control ( 20041166)
- Inflammatory bowel disease ( 28067908)
- Iron status biomarkers (iron levels) ( 28334935)
- Joint mobility (Beighton score) ( 27182965)
- Longevity ( 30294719)
- Lung cancer ( 31577861 28604730)
- Lung cancer in ever smokers ( 28604730)
- Lupus nephritis in systemic lupus erythematosus ( 24925725)
- Migraine ( 27322543)
- Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
- Obesity-related traits ( 23251661)
- Objective response to lithium treatment in bipolar disorder ( 26503763)
- Prostate cancer ( 23535732)
- Reticulocyte count ( 32888494)
- Reticulocyte fraction of red cells ( 27863252)
- Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
- Schizophrenia ( 23894747 19571808 30285260)
- Soluble receptor for advanced glycation end-product levels ( 26083729)
- Squamous cell lung carcinoma ( 28604730)
- Systemic lupus erythematosus ( 32771030 21408207)
- Systemic sclerosis ( 21779181)
- Takayasu arteritis ( 25604533)
- Type 1 diabetes (age at diagnosis) ( 33179336)
- Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
- Ulcerative colitis ( 28067908 24837172)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for body mass index ( 28448500)
|
Interacting Genes |
84 interacting genes:
ACD
AHSG
AKT1
ANGPTL4
ANP32B
ARL6IP1
BCAS3
BEX1
BLM
CCDC6
CCNE1
CCNE2
CDC34
CEBPD
CUL1
DISC1
DVL1
DYRK2
EBNA1BP2
EXT1
EZH2
FANCC
FBP2
FBXO45
GALNT12
GATA2
GATA3
GFI1
GLMN
HEMGN
HEY1
HIPK2
HNRNPK
HRAS
IGFBP3
IL24
JUN
KLF10
KLF5
LINGO1
MALAT1
MAP2K1
MAPK3
MMS22L
MYB
MYC
MYCN
NANS
NIP7
NOTCH1
NOTCH4
NOX1
PLK1
PPARGC1A
PPP3R2
PRKN
PSEN1
RFLNA
SCGB3A1
SEC61B
SHC1
SHOC2
SHPRH
SIK2
SKP1
SMAD1
SNCA
SP7
SPI1
STAT3
STAT5A
STOML1
STYX
SUMF2
TGFB1
TMOD1
TRIP12
TSC22D4
USP2
WDR5
WDR97
XPA
YAP1
ZNF510
|
13 interacting genes:
DLL4
EGFL7
ELOC
FBXW7
MAML1
MAML2
MAML3
PSEN1
PSEN2
RBPJ
SMAD2
SMAD3
SMAD4
|
Entrez ID |
55294 |
4855 |
HPRD ID |
05888 |
01290 |
Ensembl ID |
ENSG00000109670
|
ENSG00000204301
|
Uniprot IDs |
G0Z2K0
Q969H0
S4R3U4
|
A0A1U9X983
Q99466
|
PDB IDs |
2OVP
2OVQ
2OVR
5IBK
5V4B
7T1Y
7T1Z
|
7OR3
7OR5
7OR7
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|