CUL1 and CHEK1

  • Number of citations of the paper that reports this interaction (PMID 16137618)
  • 76
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo)

CUL1

CHEK1

Gene Name cullin 1 checkpoint kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 55 interactors: ARIH1 BTRC CAND1 CDC34 CDCA3 CDK9 CDKN1B CENPE CHEK1 CHUK CKS1B COMMD1 COPS2 COPS5 COPS6 COPS7A COPS8 DCUN1D4 E2F1 FBXO18 FBXO25 FBXW11 FBXW2 FBXW4 FBXW7 GLMN GPS1 HIPK2 NEDD8 NFKBIA NFKBIB NFKBIE NLK NR1D2 PARK2 PPP1CA PRPF40A PSMB4 PSMD4 PTTG1 RAC2 RANBP2 RBX1 RICTOR RNF7 SENP8 SKP1 SKP2 SMAD3 THRA TRIM21 UBE2E3 UBE2F UBE2M ZC3HC1 37 interactors: AATF AKT1 APP ATM ATR BLM BRCA1 CDC25A CDC25B CDC25C CHUK CLSPN CSNK2B CUL1 CUL4A DTL FANCE HSP90AA1 LATS2 MCPH1 MDM4 PIGM PRKDC RAD51 RB1 RELA SMAD4 TIMELESS TLK1 TOPBP1 TP53 UBB USP7 XIAP XPO1 XRCC6 YWHAG
Entrez ID 8454 1111
HPRD ID 04389 04356
Ensembl ID ENSG00000055130 ENSG00000149554
Uniprot IDs B3KTW0 Q13616 B4DT73 O14757
PDB IDs 1LDJ 1LDK 1U6G 3RTR 3TDU 3TDZ 4F52 1IA8 1NVQ 1NVR 1NVS 1ZLT 1ZYS 2AYP 2BR1 2BRB 2BRG 2BRH 2BRM 2BRN 2BRO 2C3J 2C3K 2C3L 2CGU 2CGV 2CGW 2CGX 2E9N 2E9O 2E9P 2E9U 2E9V 2GDO 2GHG 2HOG 2HXL 2HXQ 2HY0 2QHM 2QHN 2R0U 2WMQ 2WMR 2WMS 2WMT 2WMU 2WMV 2WMW 2WMX 2X8D 2X8E 2X8I 2XEY 2XEZ 2XF0 2YDI 2YDJ 2YDK 2YER 2YEX 2YM3 2YM4 2YM5 2YM6 2YM7 2YM8 2YWP 3F9N 3JVR 3JVS 3NLB 3OT3 3OT8 3PA3 3PA4 3PA5 3TKH 3TKI 3U9N 4FSM 4FSN 4FSQ 4FSR 4FST 4FSU 4FSW 4FSY 4FSZ 4FT0 4FT3 4FT5 4FT7 4FT9 4FTA 4FTC 4FTI 4FTJ 4FTK 4FTL 4FTM 4FTN 4FTO 4FTQ 4FTR 4FTT 4FTU 4GH2 4HYH 4HYI 4JIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  mitotic  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  mitotic  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Difference) ?
autophagy  box  catalytic  cdk  checkpoint  complexes  cullin1  damage  degradation  downstream  endocytosis  f  fbxl20  mediates  phosphatidylinositol  promote  proteasomal  provides  ptdins3  ptdins3p  regulate  scf  skp1  sorting  transduction  ubiquitination  vacuolar  vps34 
aggressive  atr  bcss  clinically  consequences  cytoplasmic  deregulated  doxycycline  knock  lymphovascular  mb  mcf10a  mcf7  mda  personalized  phenotypes  pleomorphism  positivity  predictor  rational  restored  ser345  serine345  signalling  tumorigenic  univariate  ve 
Tagcloud (Intersection) ?
mitotic