FBXW7 and PARK2

  • Number of citations of the paper that reports this interaction (PMID 12628165)
  • 82
  • Data Source:
  • HPRD (in vitro, in vivo)

FBXW7

PARK2

Gene Name F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase parkin RBR E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ARL6IP1 CCNE1 CCNE2 CDC34 CREB3L1 CREB3L2 CUL1 EBNA1BP2 FAM101A GLMN GNB2L1 HEY1 HIPK2 JUN KIAA1875 KLF5 LINGO1 MCL1 MED13 MED13L MMS22L MYB MYC NOTCH1 NOTCH4 PARK2 PPARGC1A PSEN1 SHPRH SKP1 STOML1 SUMF2 UBE2D1 77 interactors: AIMP2 ARR3 ARRB2 ATXN3 BAG5 CASK CASP1 CASP8 CDK5 CHPF CRX CSNK1A1 CUL1 DLG1 DLX2 DNM1L DYT10 EPS15 FAM46C FBP1 FBXO7 FBXW7 GPR37 GRIN2B HEXDC IKBKG MEOX1 MEOX2 MFN1 NDUFA4L2 PAFAH1B2 PDCD2 PICK1 PRKACA PSMA1 PSMA7 PSMC5 PSMD4 RAC1 RAD1 RAD23A RANBP2 RBCK1 REL RGS2 RGS3 SEPT4 SEPT5 SIM2 SNCA SNCAIP STUB1 SYT11 TCF4 TOMM40 TOMM70A TRIP13 TUBA4A TUBB UBASH3A UBASH3B UBB UBC UBE2D2 UBE2D3 UBE2E1 UBE2G1 UBE2G2 UBE2J1 UBE2L3 UBE2L6 UBE2M UBE2N UBE2V1 UCHL1 YWHAH ZNF746
Entrez ID 55294 5071
HPRD ID 05888 03967
Ensembl ID ENSG00000109670 ENSG00000185345
Uniprot IDs B7Z2C8 G0Z2K0 Q969H0 S4R3U4 O60260 Q5VVX4
PDB IDs 2OVP 2OVQ 2OVR 1IYF 2JMO 4BM9 4I1F 4I1H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
ataxin  atp13a2  atxn3  b12  cag  cgg  chediak  coexist  cytopathies  fmr1  fragile  gaucher  gba  glucocerebrosidase  hereditary  higashi  idiopathic  joseph  kufor  levodopa  lyst  machado  parkin  parkinsonism  pn  polg1  premutation  rakeb  tremor 
Tagcloud (Difference) ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
ataxin  atp13a2  atxn3  b12  cag  cgg  chediak  coexist  cytopathies  fmr1  fragile  gaucher  gba  glucocerebrosidase  hereditary  higashi  idiopathic  joseph  kufor  levodopa  lyst  machado  parkin  parkinsonism  pn  polg1  premutation  rakeb  tremor 
Tagcloud (Intersection) ?