PEX10 and PEX19

Number of citations of the paper that reports this interaction (PMID 10704444)
47

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, in vivo)

		PEX10	PEX19
Gene Name		peroxisomal biogenesis factor 10	peroxisomal biogenesis factor 19
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane	Nucleus Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Integral Component Of Membrane Brush Border Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Peroxisome Organization Protein Import Into Peroxisome Matrix	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Membrane Biogenesis Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways			ABC-family proteins mediated transport ABCA transporters in lipid homeostasis
Drugs
Diseases
GWAS		Non-obstructive azoospermia ( 22197933)
Protein-Protein Interactions		10 interactors: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I	32 interactors: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		5192	5824
HPRD ID		04175	02610
Ensembl ID		ENSG00000157911	ENSG00000162735
Uniprot IDs		O60683	P40855
PDB IDs			2W85 2WL8 3AJB 3MK4
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Matrix Protein Import Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Very Long-chain Fatty Acid Metabolic Process Cytoplasmic Transport Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Intracellular Protein Transport Negative Regulation Of Lipid Binding DNA Ligation Involved In DNA Recombination Positive Regulation Of SUMO Transferase Activity Organelle Organization Posttranscriptional Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Protein Stability Cellular Lipid Catabolic Process Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Cellular Protein Localization Protein Transport Protein Targeting To Membrane Neuron Migration Establishment Of Protein Localization Lagging Strand Elongation Pro-B Cell Differentiation Negative Regulation Of Protein Homooligomerization Circadian Regulation Of Translation Intracellular Transport Lipid Modification Carboxylic Acid Catabolic Process Chaperone-mediated Protein Transport Protein To Membrane Docking Establishment Of Integrated Proviral Latency Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Immunoglobulin V(D)J Recombination Negative Regulation Of Protein Oligomerization	Peroxisome Organization Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Peroxisomal Membrane Transport Protein Import Peroxisome Membrane Biogenesis Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Very Long-chain Fatty Acid Catabolic Process Protein Import Into Peroxisome Membrane Organelle Organization Protein To Membrane Docking Transmembrane Transport Establishment Of Protein Localization To Organelle Fatty Acid Beta-oxidation Protein Targeting Cellular Lipid Catabolic Process Protein Localization To Organelle Regulation Of Peroxisome Size Lipid Modification Membrane Biogenesis Carboxylic Acid Catabolic Process Protein Import Into Peroxisome Matrix, Docking Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Cytoplasmic Transport Fatty Acid Alpha-oxidation Fatty Acid Metabolic Process Establishment Of Protein Localization Peroxisome Fission Intracellular Transport Protein Localization Cellular Localization Intracellular Protein Transport Transport Establishment Of Localization In Cell Establishment Of Protein Localization To Membrane Cellular Protein Localization Protein Stabilization Membrane Docking Posttranscriptional Regulation Of Gene Expression Protein Transport Positive Regulation Of Viral Genome Replication Cellular Component Assembly Regulation Of Defense Response To Virus By Host Monocarboxylic Acid Metabolic Process
Tagcloud ?			amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Difference) ?			amphipathic anchored biogenesis chaperone concerted delivers docking engagement hydrophobic hydrophobicity inserted insertion intercalation moieties peroxisome pex3 promotes prompt reconstitute segment segments sequential steps ta tail tmd translationally uncharacterized unconventional
Tagcloud (Intersection) ?