PEX10 and MKRN3

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		PEX10	MKRN3
Gene Name		peroxisomal biogenesis factor 10	makorin ring finger protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane	Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Peroxisome Organization Protein Import Into Peroxisome Matrix	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Non-obstructive azoospermia ( 22197933)
Protein-Protein Interactions		10 interactors: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I	55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W
Entrez ID		5192	7681
HPRD ID		04175	04836
Ensembl ID		ENSG00000157911	ENSG00000179455
Uniprot IDs		O60683	Q13064
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Matrix Protein Import Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Very Long-chain Fatty Acid Metabolic Process Cytoplasmic Transport Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Intracellular Protein Transport Negative Regulation Of Lipid Binding DNA Ligation Involved In DNA Recombination Positive Regulation Of SUMO Transferase Activity Organelle Organization Posttranscriptional Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Protein Stability Cellular Lipid Catabolic Process Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Cellular Protein Localization Protein Transport Protein Targeting To Membrane Neuron Migration Establishment Of Protein Localization Lagging Strand Elongation Pro-B Cell Differentiation Negative Regulation Of Protein Homooligomerization Circadian Regulation Of Translation Intracellular Transport Lipid Modification Carboxylic Acid Catabolic Process Chaperone-mediated Protein Transport Protein To Membrane Docking Establishment Of Integrated Proviral Latency Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Immunoglobulin V(D)J Recombination Negative Regulation Of Protein Oligomerization	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process
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