PEX10 and PEX5

Number of citations of the paper that reports this interaction (PMID 10837480)
17

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		PEX10	PEX5
Gene Name		peroxisomal biogenesis factor 10	peroxisomal biogenesis factor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Peroxisome Organization Protein Import Into Peroxisome Matrix	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS		Non-obstructive azoospermia ( 22197933)	IgG glycosylation ( 23382691)
Protein-Protein Interactions		10 interactors: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		5192	5830
HPRD ID		04175	02684
Ensembl ID		ENSG00000157911	ENSG00000139197
Uniprot IDs		O60683	B4DR50 B4E0T2 P50542
PDB IDs			1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Matrix Protein Import Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Very Long-chain Fatty Acid Metabolic Process Cytoplasmic Transport Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Intracellular Protein Transport Negative Regulation Of Lipid Binding DNA Ligation Involved In DNA Recombination Positive Regulation Of SUMO Transferase Activity Organelle Organization Posttranscriptional Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Protein Stability Cellular Lipid Catabolic Process Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Cellular Protein Localization Protein Transport Protein Targeting To Membrane Neuron Migration Establishment Of Protein Localization Lagging Strand Elongation Pro-B Cell Differentiation Negative Regulation Of Protein Homooligomerization Circadian Regulation Of Translation Intracellular Transport Lipid Modification Carboxylic Acid Catabolic Process Chaperone-mediated Protein Transport Protein To Membrane Docking Establishment Of Integrated Proviral Latency Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Immunoglobulin V(D)J Recombination Negative Regulation Of Protein Oligomerization	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?			behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?