LUC7L3 and ITSN2

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		LUC7L3	ITSN2
Gene Name		LUC7-like 3 (S. cerevisiae)	intersectin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding
	Biological Process	MRNA Splice Site Selection RNA Splicing	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS			Working memory ( 21107309)
Protein-Protein Interactions		8 interactors: CLK1 ITSN2 RNPS1 SRPK1 SRPK2 SRSF1 TLR10 YWHAG	75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1
Entrez ID		51747	50618
HPRD ID		16759	09193
Ensembl ID		ENSG00000108848	ENSG00000198399
Uniprot IDs		A8K3C5 J3KPP4 O95232 Q86Y74	A6H8W8 Q9NZM3
PDB IDs			1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Positive Regulation Of Viral Genome Replication MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly MRNA Export From Nucleus Regulation Of Viral Genome Replication Positive Regulation Of Viral Process DNA-templated Transcription, Termination RNA Export From Nucleus Negative Regulation Of Viral Process MRNA 3'-end Processing Nuclear Speck Organization RNA 3'-end Processing Nuclear Export MRNA Transport Nucleus Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death RNA Transport RNA Localization Regulation Of Viral Process Ribonucleoprotein Complex Assembly MRNA 5'-splice Site Recognition Regulation Of Metabolic Process Innate Immune Response Sperm Chromatin Condensation Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cellular Process Ribonucleoprotein Complex Biogenesis MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Immune Response Protein Phosphorylation Regulation Of RNA Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Defense Response Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Intersection) ?